Abstract:
The concept of oligometastasis is widely accepted for various types of solid tumors; accordingly, better outcomes can be anticipated with aggressive local interventions. The treatment of advanced hepatocellular carcinoma (HCC) with extrahepatic metastasis is systemic therapy. However, treatment responses to systemic therapy are poor. Recently, a small number of metastatic cancers (oligometastasis) have been controlled by local therapy rather than systemic therapy. Our study reports a case of a 66-year-old male patient with advanced HCC with lung metastasis, which was treated with local therapy. There were less than four metastases in the lungs, which were treated with wedge resection, radiofrequency, and radiation therapy. He repeatedly underwent local therapy for lung oligometastasis and locoregional therapy for intrahepatic HCC rather than systemic therapy; control by local therapy was possible as his liver function was preserved with Child-Turcotte-Pugh class A.
摘要:
寡转移的概念在各种类型的实体瘤中被广泛接受;因此,积极的当地干预措施可以预期更好的结果.晚期肝细胞癌(HCC)肝外转移的治疗是全身性治疗。然而,对全身治疗的治疗反应较差。最近,少数转移性癌症(寡转移)已通过局部治疗而非全身治疗得到控制.我们的研究报告了一例66岁的男性晚期肝癌患者肺转移,采用局部治疗。肺部有不到四个转移,用楔形切除术治疗,射频,和放射治疗。他反复接受局部治疗肺寡转移和局部治疗肝内HCC,而不是全身治疗;由于他的肝功能被Child-Turcotte-PughA级保留,因此可以通过局部治疗进行控制。