关键词: coagulopathy ebv epstein-barr virus infarction infectious disease infectious mononucleosis internal medicine monospot spleen splenic

来  源:   DOI:10.7759/cureus.39472   PDF(Pubmed)

Abstract:
Infectious mononucleosis (IM) is a clinical syndrome that presents as a triad of fever, pharyngitis, and lymphadenopathy. In most cases, it is caused by the Epstein-Barr virus (EBV), which spreads through upper respiratory secretions, particularly saliva, earning its name as the Kissing Disease. In most cases, IM is self-limiting and resolves in two to four weeks without significant sequelae following supportive care. Although rare, IM has been associated with several serious and sometimes life-threatening complications, involving almost any organ system. Splenic infarction is one rare complication of IM due to EBV infection. In the past, IM-induced splenic infarction in the setting of EBV was believed to be rare and mostly limited to patients with underlying hematologic comorbidities. However, we propose this condition to be more common and more likely to occur in individuals without significant medical history than previously suspected. We report a relatively healthy young male patient in his thirties, with no previous history of coagulopathy or complex medical conditions, who was found to have IM-induced splenic infarction.
摘要:
传染性单核细胞增多症(IM)是一种临床综合征,表现为发烧三联症,咽炎,和淋巴结病。在大多数情况下,它是由爱泼斯坦-巴尔病毒(EBV)引起的,通过上呼吸道分泌物传播,尤其是唾液,得名为接吻病.在大多数情况下,IM是自限性的,在支持治疗后可在两到四周内消退,没有明显的后遗症。虽然罕见,IM与一些严重的有时危及生命的并发症有关,几乎涉及任何器官系统。脾梗死是由于EBV感染引起的IM的一种罕见并发症。在过去,在EBV的情况下,IM诱导的脾梗塞被认为是罕见的,并且主要限于具有潜在血液学合并症的患者。然而,我们认为这种情况在没有重大病史的个体中比以前怀疑的更常见和更有可能发生.我们报告了一个相对健康的30多岁的年轻男性患者,没有凝血病或复杂疾病的病史,被发现患有IM诱发的脾梗死。
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