关键词: atypical kawasaki disease coronary aneurysms luminal myofibroblastic proliferation (lmp) polymorphous skin rash transthoracic echocardiography (tte)

来  源:   DOI:10.7759/cureus.39336   PDF(Pubmed)

Abstract:
Kawasaki illness is an inflammatory condition of small- to medium-sized vessels that primarily affects children. It affects the lymph nodes, skin, mucous membranes, and heart, especially the coronary arteries. Patients who lack the comprehensive clinical manifestations of classic Kawasaki disease (KD) are typically evaluated for incomplete KD. Such patients have persistent fever and lack one or more characteristic clinical signs. Here, we present a case of a 16-month-old baby presented with fever for nine days, excessive crying and irritability for four days, and refusal to feed for one day with pallor and developed lip cracking, mucositis, bilateral edema, and redness in the palms and soles followed by periungual desquamation. Lab evaluations revealed anemia, elevated white cell count, and c-reactive protein along sterile pyuria. Since the child became afebrile after ten days of illness, inflammatory marker levels decreased, and no coronary artery abnormalities were detected on 2D echocardiography, and the child was diagnosed with incomplete KD based on the clinical, laboratory, and radiological evaluations after ruling out all other possible causes. He was managed conservatively with low-dose aspirin, and the child was doing well on a two-month follow-up.
摘要:
川崎病是一种主要影响儿童的中小型血管的炎症性疾病。它会影响淋巴结,皮肤,粘膜,和心,尤其是冠状动脉.通常对缺乏经典川崎病(KD)的综合临床表现的患者进行不完全KD评估。这些患者具有持续发热并且缺乏一种或多种特征性临床体征。这里,我们介绍了一个16个月大的婴儿发烧九天,过度哭泣和烦躁四天,拒绝一天脸色苍白,嘴唇开裂,粘膜炎,双侧水肿,手掌和脚底发红,然后是甲周脱皮。实验室评估显示贫血,白细胞计数升高,和c反应蛋白沿着无菌性脓尿。由于孩子生病十天后变得发烧,炎症标志物水平下降,二维超声心动图没有检测到冠状动脉异常,根据临床诊断,孩子患有不完全KD,实验室,以及排除所有其他可能原因后的放射学评估。他接受了低剂量阿司匹林的保守治疗,孩子在两个月的随访中表现良好。
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