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Abstract：
BACKGROUND: Although the role of melanoma risk factors is well documented, their correlation with patients\' age is less frequently analyzed.
METHODS: The analysis was performed among 189 melanoma patients in different age groups, including <30 years, 31-60 years, and >60 years, to investigate the risk factors, topography, and coexistence of morphological features of 209 melanomas (dermoscopic and histopathological).
RESULTS: Among the youngest age group, no correlation with the presence of estimated risk factors was found. The most common dermoscopic pattern was spitzoid and multicomponent asymmetric. The group of middle-aged patients was the most diverse in terms of the occurrence of risk factors, solar lentiginosis, dermoscopic patterns, topography, histological subtypes, and invasiveness of melanomas. The oldest group characterized a strong correlation between solar lentiginosis, NMSC comorbidity, the prevalence of facial melanomas, the dermoscopic pattern of melanoma arising on chronic sun-damaged skin, and regression.
CONCLUSIONS: The findings regarding the presence of age-specific features in melanoma patients, especially in the youngest and middle-aged groups, might be helpful for clinicians and to target secondary prevention efforts.
METHODS: The analysis was performed among 189 melanoma patients in different age groups, including <30 years, 31-60 years, and >60 years, to investigate the risk factors, topography, and coexistence of morphological features of 209 melanomas (dermoscopic and histopathological).
RESULTS: Among the youngest age group, no correlation with the presence of estimated risk factors was found. The most common dermoscopic pattern was spitzoid and multicomponent asymmetric. The group of middle-aged patients was the most diverse in terms of the occurrence of risk factors, solar lentiginosis, dermoscopic patterns, topography, histological subtypes, and invasiveness of melanomas. The oldest group characterized a strong correlation between solar lentiginosis, NMSC comorbidity, the prevalence of facial melanomas, the dermoscopic pattern of melanoma arising on chronic sun-damaged skin, and regression.
CONCLUSIONS: The findings regarding the presence of age-specific features in melanoma patients, especially in the youngest and middle-aged groups, might be helpful for clinicians and to target secondary prevention efforts.
摘要：
背景：尽管黑色素瘤危险因素的作用已得到充分证明，它们与患者年龄的相关性分析频率较低。
方法：对189例不同年龄段的黑色素瘤患者进行分析。包括<30年，31-60岁,>60年，为了调查风险因素，地形,209例黑素瘤的形态学特征（皮肤镜和组织病理学）共存。
结果：在最年轻的年龄组中，未发现与估计危险因素的存在相关.最常见的皮肤观察模式是类皮质和多组分不对称。在危险因素的发生方面，中年患者群体是最多样化的，日光性温牙菌病，皮肤观察模式，地形,组织学亚型,和黑色素瘤的侵袭性。最古老的群体的特点是太阳温床之间的强相关性，NMSC合并症，面部黑素瘤的患病率，皮肤镜下的黑色素瘤出现在慢性阳光损伤的皮肤上，和回归。
结论：关于黑色素瘤患者存在年龄特异性特征的发现，特别是在年轻和中年群体中，可能有助于临床医生和有针对性的二级预防工作。
方法：对189例不同年龄段的黑色素瘤患者进行分析。包括<30年，31-60岁,>60年，为了调查风险因素，地形,209例黑素瘤的形态学特征（皮肤镜和组织病理学）共存。
结果：在最年轻的年龄组中，未发现与估计危险因素的存在相关.最常见的皮肤观察模式是类皮质和多组分不对称。在危险因素的发生方面，中年患者群体是最多样化的，日光性温牙菌病，皮肤观察模式，地形,组织学亚型,和黑色素瘤的侵袭性。最古老的群体的特点是太阳温床之间的强相关性，NMSC合并症，面部黑素瘤的患病率，皮肤镜下的黑色素瘤出现在慢性阳光损伤的皮肤上，和回归。
结论：关于黑色素瘤患者存在年龄特异性特征的发现，特别是在年轻和中年群体中，可能有助于临床医生和有针对性的二级预防工作。
