关键词: chronic liver disease elastography fibrosis inflammation multiparametric ultrasound share wave dispersion steatosis viscosity

来  源:   DOI:10.3390/jpm13060945   PDF(Pubmed)

Abstract:
The development of new applications in ultrasound (US) imaging in recent years has strengthened the role of this imaging technique in the management of different pathologies, particularly in the setting of liver disease. Improved B-mode imaging (3D and 4D), contrast-enhanced US (CEUS) and especially US-based elastography techniques have created the concept of multiparametric ultrasound (MP-US), a term borrowed from radiological sectional imaging. Among the new elastography techniques, shear wave dispersion is a newly developed imaging technology which enables the assessment of the shear waves\' dispersion slope. The analysis of the dispersion qualities of shear waves might be indirectly related to the tissue viscosity, thus providing biomechanical information concerning the pathologic state of the liver such as necroinflammation. Some of the most recent US devices have been embedded with software that evaluate the dispersion of shear waves/liver viscosity. In this review, the feasibility and the clinical applications of liver viscosity are reviewed based on the preliminary findings of both animal and human studies.
摘要:
近年来,超声(US)成像新应用的发展加强了这种成像技术在不同病理学管理中的作用。特别是在肝脏疾病的背景下。改进的B模式成像(3D和4D),对比增强超声(CEUS),尤其是基于US的弹性成像技术已经创造了多参数超声(MP-US)的概念,从放射断层成像中借用的术语。在新的弹性成像技术中,剪切波色散是一种新开发的成像技术,可以评估剪切波色散斜率。对剪切波的色散特性的分析可能与组织粘度间接相关,从而提供有关肝脏病理状态如坏死性炎症的生物力学信息。一些最新的美国装置已经嵌入了评估剪切波/肝粘度的分散的软件。在这次审查中,根据动物和人体研究的初步结果,综述了肝黏度的可行性和临床应用。
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