PDF(Pubmed)
Abstract：
Introduction: Currently, the increase in the percentage of obese people observed along with the development of civilization, reaching the level of a global pandemic, has forced a search for methods of effective and permanent obesity treatment. Obesity is a multifactorial disease; it coexists with many disease entities and requires multidisciplinary treatment. Obesity leads to metabolic changes in the form of metabolic syndromes, which include, among others, atherogenic dyslipidemia. The proven relationship between dyslipidemia and cardiovascular risk enforces the need to effectively improve the lipid profile of obese patients. Laparoscopic sleeve gastrectomy is a method of surgical treatment of morbid obesity which improves bariatric and metabolic parameters. The aim of the study was to assess the effectiveness of laparoscopic sleeve gastrectomy (LSG) at improving lipid profile parameters upon a 1-year follow up. Material and Methods: Bariatric parameters of 196 patients who underwent laparoscopic sleeve gastrectomy as well as the lipid profile of total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), non-NDL, and triglycerides (TG) in a 1-year observation were analyzed. Results: Improvements in bariatric parameters were observed in patients after LSG. Total cholesterol, low-density lipoprotein (LDL), triglycerides and non-HDL level decreases were observed along with an increase in high-density lipoprotein (HDL) cholesterol levels. Conclusions: Sleeve gastrectomy is an effective method of treating obesity and improving the lipid profile in obese patients.
摘要：
介绍：目前，随着文明的发展，观察到肥胖者比例的增加，达到全球大流行的程度，迫使人们寻找有效和永久的肥胖治疗方法。肥胖是一种多因素疾病；它与许多疾病实体共存，需要多学科治疗。肥胖导致代谢综合征形式的代谢变化，其中包括，其中,致动脉粥样硬化的血脂异常。血脂异常与心血管风险之间的关系已得到证实，因此需要有效改善肥胖患者的血脂状况。腹腔镜袖状胃切除术是一种手术治疗病态肥胖的方法，可改善肥胖和代谢参数。该研究的目的是评估腹腔镜袖状胃切除术（LSG）在1年随访后改善血脂参数的有效性。材料和方法：196例腹腔镜袖状胃切除术患者的减肥参数以及总胆固醇（TC）的脂质分布，高密度脂蛋白（HDL），低密度脂蛋白（LDL），非NDL，和甘油三酯（TG）在1年的观察进行了分析。结果：在LSG术后患者中观察到减肥参数的改善。总胆固醇,低密度脂蛋白（LDL），观察到甘油三酯和非HDL水平降低,同时高密度脂蛋白(HDL)胆固醇水平升高.结论:袖状胃切除术是治疗肥胖和改善肥胖患者血脂状况的有效方法。
