PDF(Pubmed)
Abstract：
OBJECTIVE: To investigate subjective efficiency outcomes after maxillomandibular advancement (MMA) surgery in obstructive sleep apnea (OSA) patients.
METHODS: A prospective cohort study was carried out between December 2016 and May 2021, including 30 severe or treatment-refractory OSA patients treated by MMA surgery. All patients answered four validated questionnaires: the Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ), Mandibular Function Impairment Questionnaire (MFIQ), and EQ-5D-3L (i.e., EQ-5D and EQ-VAS). They also answered one custom-made questionnaire (AMCSQ). Questionnaires were requested to be filled out 1 week before surgery and at least 6 months after surgery.
RESULTS: The total preoperative and postoperative scores on the questionnaires were compared. The mean total ESS (p < 0.01), FOSQ (p < 0.01), EQ-5D (p < 0.05), and EQ-VAS (p < 0.01) scores showed significant improvement, which was in accordance with an improvement in the mean postoperative apnea/hypopnea index score (p < 0.01). In contrast, the mean total MFIQ score (p < 0.01) indicated a decline in mandibular function.
CONCLUSIONS: This study confirms the hypothesis that MMA surgery in OSA patients improves outcomes, both objectively and subjectively, with the exception of postoperative mandibular function.
METHODS: A prospective cohort study was carried out between December 2016 and May 2021, including 30 severe or treatment-refractory OSA patients treated by MMA surgery. All patients answered four validated questionnaires: the Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ), Mandibular Function Impairment Questionnaire (MFIQ), and EQ-5D-3L (i.e., EQ-5D and EQ-VAS). They also answered one custom-made questionnaire (AMCSQ). Questionnaires were requested to be filled out 1 week before surgery and at least 6 months after surgery.
RESULTS: The total preoperative and postoperative scores on the questionnaires were compared. The mean total ESS (p < 0.01), FOSQ (p < 0.01), EQ-5D (p < 0.05), and EQ-VAS (p < 0.01) scores showed significant improvement, which was in accordance with an improvement in the mean postoperative apnea/hypopnea index score (p < 0.01). In contrast, the mean total MFIQ score (p < 0.01) indicated a decline in mandibular function.
CONCLUSIONS: This study confirms the hypothesis that MMA surgery in OSA patients improves outcomes, both objectively and subjectively, with the exception of postoperative mandibular function.
摘要：
目的：调查阻塞性睡眠呼吸暂停（OSA）患者上颌下颌前移（MMA）手术后的主观效率结果。
方法：在2016年12月至2021年5月之间进行了一项前瞻性队列研究，包括30例接受MMA手术治疗的重度或难治性OSA患者。所有患者回答了四个经过验证的问卷：Epworth嗜睡量表（ESS），睡眠问卷（FOSQ）的功能结果，下颌功能损害问卷(MFIQ),和EQ-5D-3L(即，EQ-5D和EQ-VAS)。他们还回答了一份定制问卷(AMCSQ)。要求在手术前1周和手术后至少6个月填写问卷。
结果：比较问卷术前和术后总评分。平均总ESS(p<0.01)，FOSQ(p<0.01)，EQ-5D（p<0.05），EQ-VAS(p<0.01)评分显著改善,这与平均术后呼吸暂停/呼吸不足指数评分的改善一致（p<0.01）。相比之下,平均MFIQ总评分(p<0.01)显示下颌骨功能下降.
结论：这项研究证实了OSA患者MMA手术改善预后的假设，客观和主观上，术后下颌功能除外。
方法：在2016年12月至2021年5月之间进行了一项前瞻性队列研究，包括30例接受MMA手术治疗的重度或难治性OSA患者。所有患者回答了四个经过验证的问卷：Epworth嗜睡量表（ESS），睡眠问卷（FOSQ）的功能结果，下颌功能损害问卷(MFIQ),和EQ-5D-3L(即，EQ-5D和EQ-VAS)。他们还回答了一份定制问卷(AMCSQ)。要求在手术前1周和手术后至少6个月填写问卷。
结果：比较问卷术前和术后总评分。平均总ESS(p<0.01)，FOSQ(p<0.01)，EQ-5D（p<0.05），EQ-VAS(p<0.01)评分显著改善,这与平均术后呼吸暂停/呼吸不足指数评分的改善一致（p<0.01）。相比之下,平均MFIQ总评分(p<0.01)显示下颌骨功能下降.
结论：这项研究证实了OSA患者MMA手术改善预后的假设，客观和主观上，术后下颌功能除外。
