PDF(Pubmed)
Abstract：
Knee osteoarthritis (KOA) is one of the main problems of an aging society in terms of incidence, impairment to the quality of daily living (QOL), and economics. The main aim of this study was to verify the usefulness, in practical terms, of applying the existing diagnostic criteria of early knee osteoarthritis (EKOA). The secondary objective of this project was to evaluate the clinical progression of healthy subjects (HS) at risk of osteoarthritis and of patients with diagnosed EKOA. A cross-sectional longitudinal pilot study was carried out, in which 105 participants were classified as EKOA patients or HS according to the diagnostic criteria. Measures of disability, pain, and self-reported variables were assessed. Two follow-ups were performed in order to assess the diagnoses and radiological progression, and the clinical progression was evaluated using self-reported measures. Following the current diagnostic criteria, the participants were divided into EKOA and HS. Most of the participants did not present changes in their classification, although some subjects were reclassified as EKOA or HS in the follow-ups which were performed. The current classification criteria for EKOA based on self-reported measures, radiological findings, and clinical conditions such as pain could lead to a misdiagnosis of this process, as fluctuations in the classifications of patients according to their conditions were found during follow up.
摘要：
膝关节骨性关节炎(KOA)是老龄化社会的主要发病问题之一,对日常生活质量(QOL)的损害，和经济学。本研究的主要目的是验证其有用性，实际上,应用现有的早期膝关节骨性关节炎(EKOA)诊断标准。该项目的次要目标是评估有骨关节炎风险的健康受试者（HS）和诊断为EKOA的患者的临床进展。进行了横截面纵向试点研究，其中105名参与者根据诊断标准分为EKOA患者或HS.残疾的措施，疼痛,和自我报告的变量进行了评估。进行了两次随访，以评估诊断和放射学进展，并使用自我报告指标评估临床进展.按照目前的诊断标准，参与者分为EKOA和HS.大多数参与者在他们的分类中没有出现变化，尽管在进行的随访中，一些受试者被重新分类为EKOA或HS。目前的EKOA分类标准是基于自我报告的措施，放射学发现，疼痛等临床症状可能导致误诊，因为在随访过程中发现了根据患者病情分类的波动。
