PDF(Pubmed)
Abstract：
Angiostrongylus cantonensis is a metastrongyloid nematode and the etiologic agent of angiostrongyliasis, a disease characterized by eosinophilic meningitis. This emerging zoonotic parasite has undergone great expansion, including in some regions of Europe and America. In the Canary Islands, the parasite was first discovered parasitizing Rattus rattus on the island of Tenerife in 2010. To date, the distribution of this parasite in the Canary Islands has been restricted to the northern zone and the main cities of Tenerife. Using molecular tools for the sentinel species present in the Canary Islands, this study confirmed the presence of the nematode on two other islands in the Canary Archipelago: La Gomera and Gran Canaria. Furthermore, this emerging parasite was detected, besides in the common definitive host R. rattus, in wild Mus musculus and Felis catus and in four terrestrial gastropod species, Limacus flavus, Milax gagates, Insulivitrina emmersoni, and Insulivitrina oromii, two of them endemic to La Gomera, for the first time, increasing the number of non-definitive host species. This study reinforces the expansion character of A. cantonensis and highlights the importance of knowledge about sentinel species for identifying new transmission locations that help prevent and control the transmission of the parasite and, thus, prevent public health problems.
摘要：
广州管圆线虫是一种中圆线虫，是血管圆线虫病的病因，一种以嗜酸性粒细胞性脑膜炎为特征的疾病。这种新兴的人畜共患寄生虫经历了巨大的扩张，包括在欧洲和美国的一些地区。在加那利群岛,该寄生虫于2010年在特内里费岛上首次发现了寄生Rattusrattus。迄今为止,这种寄生虫在加那利群岛的分布仅限于北部地区和特内里费岛的主要城市。使用分子工具研究加那利群岛中存在的前哨物种，这项研究证实了在加那利群岛的另外两个岛屿上存在线虫：LaGomera和GranCanaria。此外，发现了这种新出现的寄生虫，除了在共同的确定宿主R.rattus中，在野生Musmusculus和Feliscatus以及四种陆生腹足动物中，白马草,MilaxGagates,InsulivitrinaEmmersoni,还有InsulivitrinaOromii,其中两个是戈麦拉特有的，第一次,增加非确定宿主物种的数量。这项研究加强了A.cantonensis的扩展特征，并强调了有关哨兵物种的知识对于识别有助于预防和控制寄生虫传播的新传播位置的重要性，因此，预防公共卫生问题。
