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Abstract：
The alteration in the shape of the femoral neck is an important radiographic sign for scoring canine hip dysplasia (CHD). Previous studies have reported that the femoral neck thickness (FNT) is greater in dogs with hip joint dysplasia, becoming progressively thicker with disease severity. The main objective of this work was to describe a femoral neck thickness index (FNTi) to quantify FNT and to study its association with the degree of CHD using the Fédération Cynologique Internationale (FCI) scheme. A total of 53 dogs (106 hips) were randomly selected for this study. Two examiners performed FNTi estimation to study intra- and inter-examiner reliability and agreement. The paired t-test, the Bland-Altman plots, and the intraclass correlation coefficient showed excellent agreement and reliability between the measurements of the two examiners and the examiners\' sessions. All joints were scored in five categories by an experienced examiner according to FCI criteria. The results from examiner 1 were compared between FCI categories. Hips that were assigned an FCI grade of A (n = 19), B (n = 23), C (n = 24), D (n = 24), and E (n = 16) had a mean ± standard deviation FNTi of 0.809 ± 0.024, 0.835 ± 0.044, 0.868 ± 0.022, 0.903 ± 0.033, and 0.923 ± 0.068, respectively (ANOVA, p < 0.05). Therefore, these results show that FNTi is a parameter capable of evaluating proximal femur bone modeling and that it has the potential to enrich conventional CHD scoring criteria if incorporated into a computer-aided diagnosis capable of detecting CHD.
摘要：
股骨颈形状的改变是对犬髋关节发育不良（CHD）进行评分的重要影像学标志。先前的研究报道，股骨颈厚度（FNT）在髋关节发育不良的狗中更大，随着疾病的严重程度逐渐变厚。这项工作的主要目的是描述股骨颈厚度指数（FNTi）以量化FNT，并使用国际妇科医生联合会（FCI）方案研究其与CHD程度的关联。随机选择总共53只狗(106髋)用于本研究。两名审查员进行了FNTi估计，以研究审查员内和审查员间的可靠性和一致性。配对t检验，Bland-Altman的阴谋,并且组内相关系数在两个审查员和审查员的测量结果之间显示出极好的一致性和可靠性。所有关节均由经验丰富的考官根据FCI标准分为五类。在FCI类别之间比较了审查员1的结果。被分配FCI等级为A的髋关节（n=19），B（n=23），C（n=24），D(n=24),和E（n=16）的平均值±标准偏差FNTi分别为0.809±0.024、0.835±0.044、0.868±0.022、0.903±0.033和0.923±0.068（方差分析，p<0.05)。因此,这些结果表明,FNTi是一个能够评估股骨近端骨建模的参数,如果将FNTi纳入能够检测CHD的计算机辅助诊断中,它有可能丰富常规CHD评分标准.
