PDF(Pubmed)
Abstract：
UNASSIGNED: The study worked with depressive symptoms, anxiety score and cognitive functions in obstructive sleep apnea (OSA) patients treated with CPAP.
UNASSIGNED: Eighty-one subjects with OSA and without psychiatric comorbidity were treated with CPAP for one year and completed the following scales and cognitive tests: Trail Making Test, Verbal Fluency Test, d2 Test, Beck Depression Inventory-II and Beck Anxiety Inventory. MINI ruled out psychiatric disorder. At the two months check-up, subjects were re-evaluated for depressive and anxiety symptoms, and after one year of CPAP treatment, subjects repeated cognitive tests and scales. Data about therapy adherence and effectiveness were obtained from the patient\'s CPAP machines.
UNASSIGNED: The study was completed by 59 CPAP adherent patients and eight non-adherent patients. CPAP therapy effectiveness was verified in all patients by decreasing the apnea-hypopnoea index below 5 and/or 10% of baseline values. The adherent patients significantly improved depressive and anxiety symptoms. There was also an improvement in overall performance in the attention test; however, performance in many individual items did not change. The adherent patients also improved verbal fluency and in the Part B of the Trail making test. The non-adherent group significantly increased the number of mistakes made in the d2 test; other results were non-significant.
UNASSIGNED: According to our results, OSA patients\' mood, anxiety and certain cognitive domains improved during the one-year therapy with CPAP.
UNASSIGNED: NCT03866161.
UNASSIGNED: Eighty-one subjects with OSA and without psychiatric comorbidity were treated with CPAP for one year and completed the following scales and cognitive tests: Trail Making Test, Verbal Fluency Test, d2 Test, Beck Depression Inventory-II and Beck Anxiety Inventory. MINI ruled out psychiatric disorder. At the two months check-up, subjects were re-evaluated for depressive and anxiety symptoms, and after one year of CPAP treatment, subjects repeated cognitive tests and scales. Data about therapy adherence and effectiveness were obtained from the patient\'s CPAP machines.
UNASSIGNED: The study was completed by 59 CPAP adherent patients and eight non-adherent patients. CPAP therapy effectiveness was verified in all patients by decreasing the apnea-hypopnoea index below 5 and/or 10% of baseline values. The adherent patients significantly improved depressive and anxiety symptoms. There was also an improvement in overall performance in the attention test; however, performance in many individual items did not change. The adherent patients also improved verbal fluency and in the Part B of the Trail making test. The non-adherent group significantly increased the number of mistakes made in the d2 test; other results were non-significant.
UNASSIGNED: According to our results, OSA patients\' mood, anxiety and certain cognitive domains improved during the one-year therapy with CPAP.
UNASSIGNED: NCT03866161.
摘要：
■这项研究对抑郁症状有效，阻塞性睡眠呼吸暂停（OSA）患者的焦虑评分和认知功能。
■81名患有OSA且无精神病合并症的受试者接受CPAP治疗一年，并完成以下量表和认知测试：跟踪测试，口语流利度测试,d2试验,贝克抑郁量表-Ⅱ和贝克焦虑量表。MINI排除了精神疾病。在两个月的体检中，重新评估受试者的抑郁和焦虑症状，经过一年的CPAP治疗，受试者重复认知测试和量表。有关治疗依从性和有效性的数据来自患者的CPAP机器。
■该研究由59名CPAP粘附患者和8名非粘附患者完成。通过将呼吸暂停低通气指数降低到基线值的5和/或10％以下，在所有患者中验证了CPAP治疗的有效性。坚持患者的抑郁和焦虑症状明显改善。注意力测试的整体表现也有所改善；然而，许多单个项目的性能没有变化。在Trail制作测试的B部分中，粘附的患者还改善了言语流畅性。非粘附组显着增加了d2测试中的错误数量；其他结果无统计学意义。
■根据我们的结果，OSA患者的情绪,在一年的CPAP治疗期间，焦虑和某些认知领域得到改善。
■NCT03866161。
■81名患有OSA且无精神病合并症的受试者接受CPAP治疗一年，并完成以下量表和认知测试：跟踪测试，口语流利度测试,d2试验,贝克抑郁量表-Ⅱ和贝克焦虑量表。MINI排除了精神疾病。在两个月的体检中，重新评估受试者的抑郁和焦虑症状，经过一年的CPAP治疗，受试者重复认知测试和量表。有关治疗依从性和有效性的数据来自患者的CPAP机器。
■该研究由59名CPAP粘附患者和8名非粘附患者完成。通过将呼吸暂停低通气指数降低到基线值的5和/或10％以下，在所有患者中验证了CPAP治疗的有效性。坚持患者的抑郁和焦虑症状明显改善。注意力测试的整体表现也有所改善；然而，许多单个项目的性能没有变化。在Trail制作测试的B部分中，粘附的患者还改善了言语流畅性。非粘附组显着增加了d2测试中的错误数量；其他结果无统计学意义。
■根据我们的结果，OSA患者的情绪,在一年的CPAP治疗期间，焦虑和某些认知领域得到改善。
■NCT03866161。
