Abstract：
OBJECTIVE: To provide an overview of the incidence of knee donor -site morbidity after autologous osteochondral mosaicplasty.
METHODS: A comprehensive search was conducted in PubMed, EMbase, Wanfang Medical Network, and CNKI databases from January 2010 to April 20, 2021. Relevant literature was selected based on predefined inclusion and exclusion criteria, and data were evaluated and extracted. The correlation between the number and size of transplanted osteochondral columns and donor-site morbidity was analyzed.
RESULTS: A total of 13 literatures were included, comprising a total of 661 patients. Statistical analysis revealed an incidence of knee donor-site morbidity at 8.6% (57/661), with knee pain being the most common complaint, accounting for 4.2%(28/661). There was no significant correlation between the number of osteochondral columns and postoperative donor-site incidence (P=0.424, N=10), nor between the diameter size of osteochondral columns and postoperative donor-site incidence(P=0.699, N=7).
CONCLUSIONS: Autologous osteochondral mosaicplasty is associated with a considerable incidence of knee donor-site morbidity, with knee pain being the most frequent complaint. There is no apparent correlation between donor-site incidence and the number and size of transplanted osteochondral columns. Donors should be informed about the potential risks.
METHODS: A comprehensive search was conducted in PubMed, EMbase, Wanfang Medical Network, and CNKI databases from January 2010 to April 20, 2021. Relevant literature was selected based on predefined inclusion and exclusion criteria, and data were evaluated and extracted. The correlation between the number and size of transplanted osteochondral columns and donor-site morbidity was analyzed.
RESULTS: A total of 13 literatures were included, comprising a total of 661 patients. Statistical analysis revealed an incidence of knee donor-site morbidity at 8.6% (57/661), with knee pain being the most common complaint, accounting for 4.2%(28/661). There was no significant correlation between the number of osteochondral columns and postoperative donor-site incidence (P=0.424, N=10), nor between the diameter size of osteochondral columns and postoperative donor-site incidence(P=0.699, N=7).
CONCLUSIONS: Autologous osteochondral mosaicplasty is associated with a considerable incidence of knee donor-site morbidity, with knee pain being the most frequent complaint. There is no apparent correlation between donor-site incidence and the number and size of transplanted osteochondral columns. Donors should be informed about the potential risks.
摘要：
目的：对自体骨软骨镶嵌术后膝关节供体部位发病率进行综述。
方法：在PubMed中进行了全面搜索，EMBase,万方医疗网,以及2010年1月至2021年4月20日的CNKI数据库。根据预定义的纳入和排除标准选择相关文献，并对数据进行了评估和提取。分析了移植骨软骨柱的数量和大小与供体部位发病率之间的相关性。
结果：共纳入13篇文献，共661名患者。统计分析显示膝关节供体部位发病率为8.6%(57/661),膝盖疼痛是最常见的症状，占4.2%(28/661)。骨软骨柱数与术后供体部位发生率无显著相关性(P=0.424,N=10),骨软骨柱直径大小与术后供体部位发生率之间也无差异(P=0.699,N=7)。
结论：自体骨软骨镶嵌成形术与膝关节供体部位发病率相当高有关，膝盖疼痛是最常见的主诉。供体部位的发生率与移植骨软骨柱的数量和大小之间没有明显的相关性。捐助者应了解潜在风险。
方法：在PubMed中进行了全面搜索，EMBase,万方医疗网,以及2010年1月至2021年4月20日的CNKI数据库。根据预定义的纳入和排除标准选择相关文献，并对数据进行了评估和提取。分析了移植骨软骨柱的数量和大小与供体部位发病率之间的相关性。
结果：共纳入13篇文献，共661名患者。统计分析显示膝关节供体部位发病率为8.6%(57/661),膝盖疼痛是最常见的症状，占4.2%(28/661)。骨软骨柱数与术后供体部位发生率无显著相关性(P=0.424,N=10),骨软骨柱直径大小与术后供体部位发生率之间也无差异(P=0.699,N=7)。
结论：自体骨软骨镶嵌成形术与膝关节供体部位发病率相当高有关，膝盖疼痛是最常见的主诉。供体部位的发生率与移植骨软骨柱的数量和大小之间没有明显的相关性。捐助者应了解潜在风险。
