PDF(Pubmed)
Abstract：
UNASSIGNED: Massive pulmonary embolism (PE) is a life-threatening complication of major surgery with a mortality rate of up to 50%. Extracorporeal membrane oxygenation (ECMO) is primarily used for respiratory and circulatory support. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is used to stabilize patients with acute massive PE. Acute brain injury, vascular disease, and immunosuppression are contraindications to ECMO, as stated in the 2021 Extracorporeal Life Support Organization guidelines.
UNASSIGNED: We report a case of a patient with craniocerebral trauma whose postoperative course was complicated by massive PE and subsequent cardiac arrest that required urgent VA-ECMO, followed by anticoagulation with heparin. The patient showed hemodynamic improvement and was discharged 68 days after hospitalization.
UNASSIGNED: ECMO has gradually been accepted for patients with craniocerebral injuries. The safety and effectiveness of ECMO in patients with craniocerebral injury, along with the optimal duration of ECMO and anticoagulation strategies, require further study.
UNASSIGNED: We report a case of a patient with craniocerebral trauma whose postoperative course was complicated by massive PE and subsequent cardiac arrest that required urgent VA-ECMO, followed by anticoagulation with heparin. The patient showed hemodynamic improvement and was discharged 68 days after hospitalization.
UNASSIGNED: ECMO has gradually been accepted for patients with craniocerebral injuries. The safety and effectiveness of ECMO in patients with craniocerebral injury, along with the optimal duration of ECMO and anticoagulation strategies, require further study.
摘要：
■大规模肺栓塞（PE）是大手术的危及生命的并发症，死亡率高达50％。体外膜氧合（ECMO）主要用于呼吸和循环支持。静脉动脉体外膜氧合（VA-ECMO）用于稳定急性大面积PE患者。急性脑损伤,血管疾病,免疫抑制是ECMO的禁忌症，正如2021年体外生命支持组织指南所述。
我们报告了一例颅脑外伤患者，其术后病程并发大量PE和随后的心脏骤停，需要紧急VA-ECMO，然后用肝素抗凝。患者血流动力学改善，住院68天后出院。
■颅脑损伤患者已逐渐接受ECMO。颅脑损伤患者ECMO的安全性和有效性,随着ECMO和抗凝策略的最佳持续时间，需要进一步研究。
我们报告了一例颅脑外伤患者，其术后病程并发大量PE和随后的心脏骤停，需要紧急VA-ECMO，然后用肝素抗凝。患者血流动力学改善，住院68天后出院。
■颅脑损伤患者已逐渐接受ECMO。颅脑损伤患者ECMO的安全性和有效性,随着ECMO和抗凝策略的最佳持续时间，需要进一步研究。
