PDF(Pubmed)
Abstract：
Desmoid tumors are a rare form of cancer, which show locally aggressive invasion of surrounding tissues and may occur anywhere in the body. Treatment options comprise conservative watch and wait strategies as tumors may show spontaneous regression as well as surgical resection, radiation therapy, nonsteroidal anti-inflammatory drugs (NSAID), chemotherapy, or local thermoablative approaches for progressive disease. The latter comprises cryotherapy, radiofrequency, microwave ablation, or thermal ablation with high intensity focused ultrasound (HIFU) as the only entirely non-invasive option. This report presents a case where a desmoid tumor at the left dorsal humerus was 2 times surgically resected and, after recurrence, thermally ablated with HIFU under magnetic resonance image-guidance (MR-HIFU). In our report, we analyze tumor volume and/or pain score during standard of care (2 years) and after HIFU treatment over a 4-year follow-up period. Results showed MR-HIFU treatment led to complete tumor remission and pain response.
摘要：
纤维瘤是一种罕见的癌症，显示对周围组织的局部侵袭性侵入，可能发生在身体的任何地方。治疗选择包括保守观察和等待策略，因为肿瘤可能显示自发消退以及手术切除，放射治疗,非甾体抗炎药（NSAID），化疗,或局部热消融治疗进行性疾病。后者包括冷冻疗法，射频,微波消融，或热消融高强度聚焦超声（HIFU）作为唯一的完全非侵入性的选择。本报告介绍了一个病例，其中左肱骨背侧硬纤维瘤被手术切除2次，复发后,在磁共振图像引导(MR-HIFU)下用HIFU热消融。在我们的报告中,我们分析了标准治疗期间(2年)和4年随访期间HIFU治疗后的肿瘤体积和/或疼痛评分.结果显示MR-HIFU治疗导致肿瘤完全缓解和疼痛反应。
