Abstract：
Quorum sensing (QS) is a communication mechanism between microorganisms originally found in bacteria. In recent years, an important QS mechanism has been discovered in the field of fungi, namely, the lipoxygenase compound oxylipin of arachidonic acid acts as a QS molecule in life cycle control, particularly in the sexual and asexual development of fungi. However, the role of oxylipins in mediating eukaryotic communication has not been previously described. In this paper, we review the regulatory role of oxylipins and the underlying mechanisms and discuss the potential for application in major fungi. The role of oxylipin as a fungal quorum-sensing molecule is the main focus of the review. Besides, the quorum regulation of fungal morphological transformation, biofilm formation, virulence factors, secondary metabolism, infection, symbiosis, and other physiological behaviors are discussed. Moreover, future prospectives and applications are elaborated as well.
摘要：
群体感应（QS）是最初在细菌中发现的微生物之间的通信机制。近年来,在真菌领域已经发现了一种重要的QS机制,即,花生四烯酸的脂氧合酶化合物oxylipin在生命周期控制中充当QS分子，特别是在真菌的性和无性发育中。然而,以前尚未描述过氧脂素在介导真核通讯中的作用。在本文中,我们回顾了氧化脂素的调节作用和潜在的机制，并讨论了在主要真菌中的应用潜力。oxylipin作为真菌群体感应分子的作用是该综述的主要重点。此外,真菌形态转化的群体调节，生物膜的形成，毒力因子，次生代谢,感染,共生,和其他生理行为进行了讨论。此外，并阐述了未来的前景和应用。
