关键词: child protection diabetes in pregnancy epidemiology health policy

来  源:   DOI:10.1136/bmjopen-2020-042476   PDF(Pubmed)

Abstract:
OBJECTIVE: The primary purpose was to measure the birth weight of infants of mothers with gestational diabetes (IMGDs) at different gestational ages to develop new reference charts and curves for them. A further purpose was to compare them with those of 159 334 infants in China to provide more accurate reference charts for the diagnosis of suspected abnormal birth weight of IMGDs. The final purpose was to evaluate the key periods for such mothers to control their weight in line with the difference of fetal weight of each two neighbouring gestational ages.
METHODS: A specialised hospital in South China PARTICIPANTS: IMGDs born here from January 2014 to December 2018.
UNASSIGNED: Birth weight, gestational ages of IMGDs, gender and year of birth.
RESULTS: Data of 14 311 singleton live births at the gestational weeks 25-42 here were collected. The proportions of low birth weight, normal birth weight and macrosomia were 7.26%, 87.04%, and 5.70%, respectively. The proportions of small for gestational age, appropriate for gestational age and large for gestational age were 5.69%, 84.42% and 9.89%, respectively. In the macrosomia group, the mean of all birth weight in 2017 decreased for the first time since 2014. Both the means of birth weight of male infants at gestational weeks 36-41 and of female at weeks 38-40 were greater than that of the 159 334 infants. The increase of each weekly mean of IMGDs at gestational weeks 27-31 and 33-35 was >10% compared with the former. Based on this, new reference charts of birth weight for IMGDs in terms of different gestational age and gender were formulated.
CONCLUSIONS: These charts may be applied as reference for more accurate diagnosis and quick treatment of abnormal birth weight. This study showed that the identification of key periods for fetal weight gain was helpful for the management of the weight of women with gestational diabetes.
摘要:
目的:主要目的是测量妊娠期糖尿病(IMGD)母亲在不同胎龄下的出生体重,以建立新的参考图表和曲线。进一步的目的是将它们与中国159334名婴儿的婴儿进行比较,以提供更准确的参考图表,以诊断疑似IMGD的异常出生体重。最终目的是评估这些母亲根据每两个相邻胎龄的胎儿体重差异控制体重的关键时期。
方法:华南地区某专科医院参与者:2014年1月至2018年12月在此出生的IMGD。
出生体重,IMGD的胎龄,性别和出生年份。
结果:此处收集了25-42孕周14311例单胎活产的数据。低出生体重的比例,正常出生体重和巨大儿占7.26%,87.04%,5.70%,分别。小于胎龄的比例,适合胎龄和大胎龄的是5.69%,84.42%和9.89%,分别。在巨大儿组中,2017年所有出生体重的平均值自2014年以来首次下降。36-41孕周男性婴儿和38-40孕周女性婴儿的出生体重平均值均大于159334例婴儿。与前者相比,在妊娠27-31周和33-35周时,IMGD的每周平均值增加>10%。基于此,根据不同胎龄和性别,制定了IMGD出生体重的新参考图表。
结论:这些图表可作为更准确诊断和快速治疗出生体重异常的参考。这项研究表明,确定胎儿体重增加的关键时期有助于管理妊娠期糖尿病妇女的体重。
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