Abstract：
UNASSIGNED: To assess visual acuity (VA) and stereoacuity (SA) improvements in children with amblyopia treated with either binocular dichoptic treatment or patching treatment.
UNASSIGNED: In this pilot prospective coherent study, 34 participants between 4 and 9 years of age with unilateral anisometropic amblyopia and without history of prior amblyopia treatment were enrolled into three groups. Full treatment group (FTG; n = 12): participants were prescribed the binocular dichoptic treatment to watch for 90 minutes per day, 5 days a week. Part-time treatment group (PTTG; n = 8): participants were prescribed the same binocular treatment as FTG, 90 minutes per day, 3 days per week. Patching treatment group (PTG; n = 14): participants wore an adhesive patch over the dominant eye for 2 hours per day, 7 days per week. Amblyopic-eye distance visual acuity (DVA), near visual acuity (NVA) and SA were evaluated at baseline, 4, 8, and 12 weeks.
UNASSIGNED: At 12 weeks, mean amblyopic-eye DVA improved 1.8 lines (95% CI, 1.1-2.5) in FTG, 1.5 lines (95% CI, 0.4-2.7) in PTTG and 3.0 lines (95% CI, 2.0-4.0) in PTG. The amblyopic-eye NVA improved 2.9 lines (95% CI, 2.4-3.5) in FTG, 1.7 lines (95% CI, 0.5-3.0) in PTTG and 2.8 lines (95% CI, 1.8-3.9) in PTG. The SA improved 0.38 log-arcseconds (95% CI, 0.24-0.53) in FTG, 0.59 log-arcseconds (95% CI, 0.36-0.82) in PTTG and 0.40 log-arcseconds (95% CI, 0.13-0.67) in PTG. No significant differences were found in DVA, NVA or SA improvement between FTG and PTG at 12 weeks.
UNASSIGNED: VA and SA after binocular dichoptic treatment produced a similar therapeutic outcome to patching, suggesting a potential value for binocular therapy when treating anisometropic moderate degree of Children\'s amblyopia.
UNASSIGNED: In this pilot prospective coherent study, 34 participants between 4 and 9 years of age with unilateral anisometropic amblyopia and without history of prior amblyopia treatment were enrolled into three groups. Full treatment group (FTG; n = 12): participants were prescribed the binocular dichoptic treatment to watch for 90 minutes per day, 5 days a week. Part-time treatment group (PTTG; n = 8): participants were prescribed the same binocular treatment as FTG, 90 minutes per day, 3 days per week. Patching treatment group (PTG; n = 14): participants wore an adhesive patch over the dominant eye for 2 hours per day, 7 days per week. Amblyopic-eye distance visual acuity (DVA), near visual acuity (NVA) and SA were evaluated at baseline, 4, 8, and 12 weeks.
UNASSIGNED: At 12 weeks, mean amblyopic-eye DVA improved 1.8 lines (95% CI, 1.1-2.5) in FTG, 1.5 lines (95% CI, 0.4-2.7) in PTTG and 3.0 lines (95% CI, 2.0-4.0) in PTG. The amblyopic-eye NVA improved 2.9 lines (95% CI, 2.4-3.5) in FTG, 1.7 lines (95% CI, 0.5-3.0) in PTTG and 2.8 lines (95% CI, 1.8-3.9) in PTG. The SA improved 0.38 log-arcseconds (95% CI, 0.24-0.53) in FTG, 0.59 log-arcseconds (95% CI, 0.36-0.82) in PTTG and 0.40 log-arcseconds (95% CI, 0.13-0.67) in PTG. No significant differences were found in DVA, NVA or SA improvement between FTG and PTG at 12 weeks.
UNASSIGNED: VA and SA after binocular dichoptic treatment produced a similar therapeutic outcome to patching, suggesting a potential value for binocular therapy when treating anisometropic moderate degree of Children\'s amblyopia.
摘要：
■评估双眼双目治疗或补片治疗弱视儿童的视力（VA）和立体视力（SA）改善。
■在这项前瞻性相关研究中，34名年龄在4至9岁之间的单侧屈光参差性弱视且没有弱视治疗史的参与者被纳入三组。完全治疗组（FTG;n=12）：参与者每天接受双眼双目治疗90分钟，一周五天。非全日制治疗组（PTTG;n=8）：参与者被规定与FTG相同的双眼治疗，每天90分钟,每周3天。贴片治疗组（PTG;n=14）：参与者每天在优势眼上佩戴贴片2小时，每周7天。弱视眼距离视力（DVA），在基线时评估近视敏度（NVA）和SA，4、8和12周。
■在12周时，平均弱视眼DVA在FTG中改善了1.8行（95％CI，1.1-2.5），PTTG中有1.5行（95%CI，0.4-2.7），PTG中有3.0行（95%CI，2.0-4.0）。弱视NVA在FTG中提高了2.9行（95％CI，2.4-3.5），PTTG中有1.7行（95%CI，0.5-3.0），PTG中有2.8行（95%CI，1.8-3.9）。SA在FTG中提高了0.38对数弧秒(95%CI，0.24-0.53)，PTTG为0.59对数弧秒（95％CI，0.36-0.82），PTG为0.40对数弧秒（95％CI，0.13-0.67）。DVA没有发现显著差异，在12周时，FTG和PTG之间的NVA或SA改善。
■双眼双目治疗后的VA和SA产生了与修补相似的治疗结果，提示在治疗中度屈光参差性儿童弱视时，双眼治疗具有潜在价值。
■在这项前瞻性相关研究中，34名年龄在4至9岁之间的单侧屈光参差性弱视且没有弱视治疗史的参与者被纳入三组。完全治疗组（FTG;n=12）：参与者每天接受双眼双目治疗90分钟，一周五天。非全日制治疗组（PTTG;n=8）：参与者被规定与FTG相同的双眼治疗，每天90分钟,每周3天。贴片治疗组（PTG;n=14）：参与者每天在优势眼上佩戴贴片2小时，每周7天。弱视眼距离视力（DVA），在基线时评估近视敏度（NVA）和SA，4、8和12周。
■在12周时，平均弱视眼DVA在FTG中改善了1.8行（95％CI，1.1-2.5），PTTG中有1.5行（95%CI，0.4-2.7），PTG中有3.0行（95%CI，2.0-4.0）。弱视NVA在FTG中提高了2.9行（95％CI，2.4-3.5），PTTG中有1.7行（95%CI，0.5-3.0），PTG中有2.8行（95%CI，1.8-3.9）。SA在FTG中提高了0.38对数弧秒(95%CI，0.24-0.53)，PTTG为0.59对数弧秒（95％CI，0.36-0.82），PTG为0.40对数弧秒（95％CI，0.13-0.67）。DVA没有发现显著差异，在12周时，FTG和PTG之间的NVA或SA改善。
■双眼双目治疗后的VA和SA产生了与修补相似的治疗结果，提示在治疗中度屈光参差性儿童弱视时，双眼治疗具有潜在价值。
