PDF(Pubmed)
Abstract：
Wastewater surveillance offers a rapid evaluation of SARS-CoV-2 transmission in a community. We describe how a community group, the Yarmouth Wastewater Testing Team (YWTT), in Yarmouth, Maine, (population 8,990) utilized an asset-based community design framework to organize and manage a program to monitor SARS-CoV-2 RNA concentrations. From September 22, 2020 through June 8, 2021, the YWTT disseminated weekly reports of the wastewater results and reported COVID-19 cases within the Yarmouth postal code. After high and increasing SARS-CoV-2 RNA concentrations, the YWTT issued two community advisories to encourage extra care to reduce exposure. Correlations between SARS-CoV-2 RNA concentrations and COVID-19 cases were stronger the week after sampling, and the average of the COVID-19 cases during the week of sampling and the following week, indicating that surveillance provided advance notice of cases. A 10% increase in SARS-CoV-2 RNA concentrations was associated with a 13.29% increase in the average number of weekly reported cases of COVID-19 during the week of sampling and the following week (R2 = 0.42; p < 0.001). Adjusting for viral recovery (December 21, 2020 through June 8, 2021), improved R2 from 0.60 to 0.68. Wastewater surveillance was an effective tool for the YWTT to quickly respond to viral transmission.
摘要：
废水监测可快速评估社区中的SARS-CoV-2传播。我们描述了一个社区团体，雅茅斯废水测试小组(YWTT)，在雅茅斯,缅因州,（人口8,990）利用基于资产的社区设计框架来组织和管理监视SARS-CoV-2RNA浓度的程序。从2020年9月22日至2021年6月8日，YWTT每周发布废水结果报告，并在雅茅斯邮政编码内报告COVID-19病例。在SARS-CoV-2RNA浓度高且不断增加之后，YWTT发布了两项社区建议，以鼓励额外护理以减少暴露。采样后一周，SARS-CoV-2RNA浓度与COVID-19病例之间的相关性更强，以及取样一周和下一周COVID-19病例的平均值，表明监测提供了案件的提前通知。在采样周和下一周，SARS-CoV-2RNA浓度增加10%，每周报告的COVID-19病例平均增加13.29%(R2=0.42；p<0.001)。调整病毒恢复（2020年12月21日至2021年6月8日），将R2从0.60提高到0.68。废水监测是YWTT快速应对病毒传播的有效工具。
