PDF(Pubmed)
Abstract：
BACKGROUND: Esophagus cancer patients are at risk for malnourishment. Feeding jejunostomy is used in advanced esophagus cancer patients in order to support and supplement the patients\' nutrition needs. In dumping syndrome, the food is rapidly introduced into the intestine at a rate that is faster than normal, it is associated with both digestive system and vasoactive symptoms. Dumping syndrome has an association with both esophagus cancer patients and feeding jejunostomy. In the mid and long term, dumping syndrome is an important issue that contributes to the risk of malnourishment in advanced esophagus cancer patients. In recent studies, acupuncture was effective in regulating digestive symptoms. Acupuncture is considered to be a safe intervention, that was previously shown to be effective in treating digestive-related symptoms.
METHODS: Sixty advanced esophageal cancer patients post-feeding jejunostomy will be divided into 2 equal groups, an intervention group (n = 30) and a control group (n = 30). Patients in the intervention group will receive acupuncture using the following acupoints: ST36 (Zusanli), ST37 (Shangjuxu), ST39 (Xiajuxu), PC6 (Neiguan), LI4 (Hegu), and Liv 3 (Taichung). Patients in the control group will receive shallow acupuncture on 12 non-acupoints (sham points), 1 cm from the above mention points. Patients and assessors will be blind to trial allocation. Both groups will receive acupuncture twice a week for 6 weeks. The main outcome measurements are: body weight, BMI, Sigstad\'s score, and the Arts\' dumping questionnaire.
CONCLUSIONS: There are no previous studies that have examined the use of acupuncture on patients with dumping syndrome. This single-blind randomized control trial will investigate the effect of acupuncture on dumping syndrome in advanced esophagus cancer patients with feeding jejunostomy. The results will determine if verum acupuncture can affect dumping syndrome and prevent weight loss.
METHODS: Sixty advanced esophageal cancer patients post-feeding jejunostomy will be divided into 2 equal groups, an intervention group (n = 30) and a control group (n = 30). Patients in the intervention group will receive acupuncture using the following acupoints: ST36 (Zusanli), ST37 (Shangjuxu), ST39 (Xiajuxu), PC6 (Neiguan), LI4 (Hegu), and Liv 3 (Taichung). Patients in the control group will receive shallow acupuncture on 12 non-acupoints (sham points), 1 cm from the above mention points. Patients and assessors will be blind to trial allocation. Both groups will receive acupuncture twice a week for 6 weeks. The main outcome measurements are: body weight, BMI, Sigstad\'s score, and the Arts\' dumping questionnaire.
CONCLUSIONS: There are no previous studies that have examined the use of acupuncture on patients with dumping syndrome. This single-blind randomized control trial will investigate the effect of acupuncture on dumping syndrome in advanced esophagus cancer patients with feeding jejunostomy. The results will determine if verum acupuncture can affect dumping syndrome and prevent weight loss.
摘要：
背景：食管癌患者存在营养不良的风险。空肠吻合术用于晚期食管癌患者，以支持和补充患者的营养需求。在倾倒综合症中，食物以比正常速度快的速度迅速进入肠道，它与消化系统和血管活性症状有关。倾倒综合征与食管癌患者和进食空肠造口术有关。从中长期来看,倾倒综合征是导致晚期食管癌患者营养不良风险的重要问题。在最近的研究中,针灸有效调节消化症状。针灸被认为是一种安全的干预措施，以前被证明可以有效治疗与消化相关的症状。
方法：将60例进食后空肠吻合术的晚期食管癌患者分为2组，干预组（n=30）和对照组（n=30）。干预组患者将接受以下穴位的针刺：ST36（足三里），ST37(上巨旭),ST39(夏居旭),PC6（内关），LI4(Hegu),和丽芙3（台中）。对照组患者将接受12个非穴位（假穴位）的浅针刺，1厘米以上提到的点。患者和评估人员将对试验分配视而不见。两组都将接受为期6周的每周两次针灸。主要结果测量是：体重，BMI,Sigstad的得分,和艺术倾销问卷。
结论：以前没有研究过针灸对倾倒综合征患者的使用。这项单盲随机对照试验将研究针刺对晚期食管癌空肠吻合术患者倾倒综合征的影响。结果将确定Verum针刺是否可以影响倾倒综合征并防止体重减轻。
方法：将60例进食后空肠吻合术的晚期食管癌患者分为2组，干预组（n=30）和对照组（n=30）。干预组患者将接受以下穴位的针刺：ST36（足三里），ST37(上巨旭),ST39(夏居旭),PC6（内关），LI4(Hegu),和丽芙3（台中）。对照组患者将接受12个非穴位（假穴位）的浅针刺，1厘米以上提到的点。患者和评估人员将对试验分配视而不见。两组都将接受为期6周的每周两次针灸。主要结果测量是：体重，BMI,Sigstad的得分,和艺术倾销问卷。
结论：以前没有研究过针灸对倾倒综合征患者的使用。这项单盲随机对照试验将研究针刺对晚期食管癌空肠吻合术患者倾倒综合征的影响。结果将确定Verum针刺是否可以影响倾倒综合征并防止体重减轻。
