OK432 sclerotherapy for refractory chylous leakage after neck dissection.

OK432 硬化治疗颈淋巴结清扫术后难治性乳糜漏。

• 发表时间: 2023 Jun
• 来源期刊: J Surg Case Rep
• DOI: 10.1093/jscr/rjad310
• PMID: 37332664
• 文章类型: Case Reports
• 作者列表: Hashimoto Y,Teshima M,Yui M,Tatehara S,Iritani K,Furukawa T,Shinomiya H,Nibu KI

关键词: chylous leakage; complication; head and neck cancer; intractable; neck dissection

Abstract

Chylous leakage is a rare but serious postoperative complication of neck dissection (ND). Most chylous leakages are successfully treated either by drainage or ligation of the thoracic duct, but the resolution is occasionally prolonged. OK432 sclerotherapy is used to treat various refractory cystic diseases of the head and neck. Three patients were treated with OK432 sclerotherapy for refractory chylous leakage following ND. Case 1 involved a 77-year-old man with chylous leakage after a total laryngectomy and bilateral ND. Case 2 involved a 71-year-old woman who underwent total thyroidectomy and left ND for thyroid cancer. Case 3 involved a 61-year-old woman who underwent right ND for oropharyngeal cancer. In all patients, chylous leakage rapidly improved after OK432 injection without any complications. Our results suggest the efficacy of OK432 sclerotherapy in patients with refractory chylous leakage after ND.

摘要

乳糜漏是颈淋巴结清扫术（ND）的一种罕见但严重的术后并发症。大多数乳糜渗漏通过引流或胸导管结扎成功治疗。但是决议有时会延长。OK432硬化疗法用于治疗各种难治性头颈部囊性疾病。三名患者接受OK432硬化疗法治疗，治疗ND后难治性乳糜漏。病例1涉及一名77岁的男子，在全喉切除术和双侧ND后发生乳糜漏。病例2涉及一名71岁的女性，她接受了甲状腺全切除术，并因甲状腺癌而左ND。病例3涉及一名61岁的女性，她因口咽癌接受了右ND。在所有患者中，注射OK432后乳糜渗漏迅速改善，无任何并发症。我们的结果表明，OK432硬化疗法对ND后难治性乳糜漏患者的疗效。