关键词: Graft-versus-host disease Hematopoietic stem cell transplantation Oral manifestations Pain Quality of life

来  源:   DOI:10.1016/j.htct.2023.04.004   PDF(Pubmed)

Abstract:
Patients undergoing hematopoietic stem cell transplantation (HSCT) might present acute and late toxicities and the oral tissues are frequently affected. With the survival increasing, patients show late and long-term morbidities, and there is an important association between the general and the oral health. The first and second parts of this Consensus have showed the importance of the adequacy of oral health in the pre-HSCT, and the main alterations and oral care during the period of admission for HSCT. This third part aims to review specific themes of post-HSCT dental care, such as graft-versus-host disease (GVHD) and the pediatric patient. It also aims to review pertinent subjects, both during the HSCT period and post-HSCT, concerning quality of life, pain, cost-effectiveness, and remote care. Based on this review, it is evident the importance of the work of the dental surgeon (DS) in the follow-up and treatment of the HSCT patient, always collaborating with the whole multidisciplinary team.
摘要:
接受造血干细胞移植(HSCT)的患者可能会出现急性和晚期毒性,并且口腔组织经常受到影响。随着生存的增加,患者表现出晚期和长期的发病率,一般和口腔健康之间有重要的联系。该共识的第一部分和第二部分表明了口腔健康在HSCT之前的重要性,以及HSCT入院期间的主要改变和口腔护理。第三部分旨在回顾HSCT后牙科护理的具体主题,如移植物抗宿主病(GVHD)和儿科患者。它还旨在审查相关主题,在HSCT期间和HSCT后,关于生活质量,疼痛,成本效益,远程护理。基于这篇综述,很明显,牙科医生(DS)在HSCT患者的随访和治疗中的重要性,始终与整个多学科团队合作。
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