Abstract:
Central nervous system (CNS) phaeohyphomycosis is a rare and often fatal fungal infection. Our study reported a case series of eight CNS phaeohyphomycosis cases at our institution over the past 20 years. We did not observe the common pattern of risk factors, abscess location, or number of abscesses among them. Most patients were immunocompetent without classic risk factors for fungal infection. Early diagnosis and aggressive management with surgical intervention and prolonged antifungal therapy can lead to a favorable outcome. The study highlights the need for further research to better understand the pathogenesis and optimal management of this challenging rare infection.
摘要:
中枢神经系统(CNS)带真菌病是一种罕见且通常致命的真菌感染。在过去的20年中,我们的研究报告了我们机构的8例中枢神经系统疾病病例。我们没有观察到常见的危险因素模式,脓肿位置,或其中脓肿的数量。大多数患者具有免疫能力,没有真菌感染的经典危险因素。通过手术干预和长期抗真菌治疗的早期诊断和积极管理可以导致有利的结果。该研究强调需要进一步研究,以更好地了解这种具有挑战性的罕见感染的发病机理和最佳管理。
中枢神经系统带真菌病是一种致命的疾病。在过去的二十年中,我们在我们的机构报告了8例病例。我们描述了这些患者的详细临床表现和管理,并阐明了有关这种罕见疾病的重要临床问题。