Abstract：
OBJECTIVE: Pollakiuria is defined as a change in the pattern of daily urination. Students have mentioned wetting their pants at school as the third tragic event after the death of a parent or going blind. In this study, the effect of adding Montelukast to oxybutynin on the improvement of urinary symptoms of patients with pollakiuria was studied.
METHODS: This study was a pilot clinical trial in which children with pollakiuria aged 3-18 years old were included. These children were randomly divided into two groups of intervention (Montelukast plus oxybutynin) and the control group (only oxybutynin). At the beginning and the end of the study (after 14 days), mothers were asked about the frequency of daily urination. Finally, the gathered data were compared between two groups.
RESULTS: In the present study, 64 patients were examined in two intervention and control groups (32 in each group). The results revealed that although significant changes were observed in both groups before and after intervention, the average changes in the intervention group were significantly higher (p = 0.014).
CONCLUSIONS: The results of this study showed that adding montelukast to oxybutynin has a significant decrease in frequency of daily urination in patients with pollakiuria, although further studies are recommended in this area.
METHODS: This study was a pilot clinical trial in which children with pollakiuria aged 3-18 years old were included. These children were randomly divided into two groups of intervention (Montelukast plus oxybutynin) and the control group (only oxybutynin). At the beginning and the end of the study (after 14 days), mothers were asked about the frequency of daily urination. Finally, the gathered data were compared between two groups.
RESULTS: In the present study, 64 patients were examined in two intervention and control groups (32 in each group). The results revealed that although significant changes were observed in both groups before and after intervention, the average changes in the intervention group were significantly higher (p = 0.014).
CONCLUSIONS: The results of this study showed that adding montelukast to oxybutynin has a significant decrease in frequency of daily urination in patients with pollakiuria, although further studies are recommended in this area.
摘要：
目的：Polakiuria定义为每日排尿模式的变化。学生们提到在学校弄湿裤子是父母去世或失明后的第三次悲剧事件。在这项研究中,研究了孟鲁司特加奥昔布宁对尿频患者尿路症状改善的作用。
方法：本研究是一项试点临床试验，纳入3-18岁的尿频儿童。将这些患儿随机分为干预组(孟鲁司特加奥昔布宁)和对照组(仅奥昔布宁)。在研究开始和结束时（14天后），母亲们被问及每天排尿的频率。最后,比较两组收集的数据.
结果：在本研究中，在干预组和对照组中检查了64例患者（每组32例）。结果显示，尽管干预前后两组均有显著变化，干预组的平均变化显著高于对照组(p=0.014).
结论：这项研究的结果表明，在奥昔布宁中加入孟鲁司特可以显着降低尿频患者的每日排尿频率，尽管建议在这方面进行进一步的研究。
方法：本研究是一项试点临床试验，纳入3-18岁的尿频儿童。将这些患儿随机分为干预组(孟鲁司特加奥昔布宁)和对照组(仅奥昔布宁)。在研究开始和结束时（14天后），母亲们被问及每天排尿的频率。最后,比较两组收集的数据.
结果：在本研究中，在干预组和对照组中检查了64例患者（每组32例）。结果显示，尽管干预前后两组均有显著变化，干预组的平均变化显著高于对照组(p=0.014).
结论：这项研究的结果表明，在奥昔布宁中加入孟鲁司特可以显着降低尿频患者的每日排尿频率，尽管建议在这方面进行进一步的研究。
