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Abstract：
Background There are limited studies analyzing cutaneous lupus erythematosus (CLE) hospitalizations. In this study, we aimed to analyze baseline demographics of systemic lupus erythematosus (SLE) and CLE patients, identify the most common reasons for hospitalizations, and find out the hospitalization outcomes. Materials and methods We performed the analysis using the National (Nationwide) Inpatient Sample (NIS) database between 2016 and 2019. For the CLE cohort, data for adults aged 18 years and older with the primary or secondary diagnosis of CLE using International Classification of Disease - 10th revision (ICD-10) codes were extracted. For comparison, the SLE cohort was identified by patients aged 18 years and older with primary or secondary diagnoses of SLE using ICD-10 codes. Chi-squared test was used to compare baseline demographic characteristics. Multivariable logistic and linear regression was used to calculate outcomes of interest. Results In comparison to the SLE cohort, the CLE cohort was not only older in age and lower percentage female, but also had shorter length of stay, less total hospital charge, and the majority had Medicare as primary insurance. The SLE cohort included predominantly African American patients while the CLE cohort was majority Caucasian patients. The cardiovascular risks were more prevalent in the CLE cohort and most commonly admitted for sepsis, cardiovascular disease, and mental health disorders. Conclusion Our study highlights the importance of outpatient follow-up in CLE patients to closely monitor cardiovascular risk factors, early identification of infections, and routine mental health screenings to reduce hospitalizations and resource utilization.
摘要：
背景分析皮肤红斑狼疮（CLE）住院的研究有限。在这项研究中,我们旨在分析系统性红斑狼疮（SLE）和CLE患者的基线人口统计学，找出最常见的住院原因，并找出住院结果。材料和方法我们在2016年至2019年之间使用国家（全国）住院样本（NIS）数据库进行了分析。对于CLE队列，我们提取了使用国际疾病分类-第10次修订(ICD-10)代码诊断CLE的18岁及以上成人的数据.为了比较，SLE队列由年龄在18岁及以上且使用ICD-10编码诊断为SLE的原发性或继发性患者确定.卡方检验用于比较基线人口统计学特征。多变量逻辑和线性回归用于计算感兴趣的结果。结果与SLE队列相比，CLE队列不仅年龄较大，女性比例较低，但停留时间也较短，减去医院的总费用，大多数人将医疗保险作为主要保险。SLE队列主要包括非裔美国患者，而CLE队列主要是白种人患者。心血管风险在CLE队列中更为普遍，最常见于败血症，心血管疾病,和精神健康障碍。结论我们的研究强调了门诊随访对CLE患者密切监测心血管危险因素的重要性,早期识别感染，和常规精神健康检查，以减少住院和资源利用。
