PDF(Pubmed)
Abstract：
Infections caused by extensively drug-resistant Pseudomonas aeruginosa are difficult to treat due to limited effective treatment options. In this issue, a patient with a corneal infection caused by a Verona integron-encoded metallo-β-lactamase (VIM)- and Guiana extended-spectrum β-lactamase (GES)-coproducing P. aeruginosa strain associated with the recent artificial tears-related outbreak in the United States is described. This resistance genotype/phenotype further compromises therapeutic options, and this report provides insights into diagnostic and treatment approaches for clinicians dealing with infections due to this highly resistant P. aeruginosa.
摘要：
由广泛耐药的铜绿假单胞菌引起的感染由于有效的治疗选择有限而难以治疗。在这个问题上，描述了一例由维罗纳整合子编码的金属β-内酰胺酶(VIM)和圭亚那产超广谱β-内酰胺酶(GES)共产铜绿假单胞菌引起的角膜感染患者,该患者与美国最近发生的人工泪液相关的疫情有关.这种抗性基因型/表型进一步损害了治疗选择，本报告为临床医生处理这种高度耐药的铜绿假单胞菌感染提供了诊断和治疗方法的见解。
