Abstract：
BACKGROUND: Human papillomavirus (HPV) vaccine has immense research value in the prevention of related tumours. A huge body of work has been published in this field, which may pose difficulties for researchers aiming to investigate all the available information. However, bibliometrics can provide deep insights into this research field.
OBJECTIVE: We aimed to study HPV vaccine development, visually analyse the development status, trends, research hotspots, and frontiers of this field, and provide a reference for research on it.
METHODS: Articles were acquired from the Web of Science Core Collection. VOS viewer and CiteSpace software were used to analyse publication growth, country/region, institution, journal distribution, author, reference, and keywords, and collected burst keyword words to display research hotspots.
RESULTS: A total of 4831 references were obtained, and the annual number of publications increased fluctuating over the past decade. The United States of America ranked at the top in terms of percentage of articles. The institution with the highest number of research publications in this field was the Centers for Disease Control and Prevention. The most productive and frequently cited authors was Lauri E Markowitz. The journal with the most publications in this field was Vaccine, and the most influential journal was Paediatrics. The most frequently cited reference was \'A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women\'. Burst detection analysis of top keywords showed that \'national immunisation survey\', \'social media\', and \'hesitancy\' are the current research frontiers in this field.
CONCLUSIONS: This study provides useful information for acquiring knowledge on HPV vaccine. Research on solving the hesitation of HPV vaccination will become an academic trend in this field, which can offer guidance for more extensive and in-depth studies in the future.
OBJECTIVE: We aimed to study HPV vaccine development, visually analyse the development status, trends, research hotspots, and frontiers of this field, and provide a reference for research on it.
METHODS: Articles were acquired from the Web of Science Core Collection. VOS viewer and CiteSpace software were used to analyse publication growth, country/region, institution, journal distribution, author, reference, and keywords, and collected burst keyword words to display research hotspots.
RESULTS: A total of 4831 references were obtained, and the annual number of publications increased fluctuating over the past decade. The United States of America ranked at the top in terms of percentage of articles. The institution with the highest number of research publications in this field was the Centers for Disease Control and Prevention. The most productive and frequently cited authors was Lauri E Markowitz. The journal with the most publications in this field was Vaccine, and the most influential journal was Paediatrics. The most frequently cited reference was \'A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women\'. Burst detection analysis of top keywords showed that \'national immunisation survey\', \'social media\', and \'hesitancy\' are the current research frontiers in this field.
CONCLUSIONS: This study provides useful information for acquiring knowledge on HPV vaccine. Research on solving the hesitation of HPV vaccination will become an academic trend in this field, which can offer guidance for more extensive and in-depth studies in the future.
摘要：
背景：人乳头瘤病毒（HPV）疫苗在预防相关肿瘤方面具有巨大的研究价值。在这个领域已经发表了大量的工作，这可能给旨在调查所有可用信息的研究人员带来困难。然而,文献计量学可以为这一研究领域提供深刻的见解。
目的：我们旨在研究HPV疫苗的开发，直观地分析发展状况，趋势,研究热点,和这个领域的前沿，为其研究提供参考。
方法：文章来自WebofScienceCoreCollection。VOS查看器和CiteSpace软件用于分析出版物增长，国家/地区,机构,日记帐分布，作者,参考，和关键词，并收集突发关键词来展示研究热点。
结果：共获得4831个参考文献，过去十年来，每年的出版物数量不断增加。美利坚合众国在文章百分比方面排名最高。该领域研究出版物数量最多的机构是疾病控制和预防中心。最有生产力和经常被引用的作者是LauriEMarkowitz。该领域出版物最多的杂志是疫苗，最有影响力的杂志是儿科。最常引用的参考文献是“抗女性感染和上皮内瘤变的9价HPV疫苗”。对顶级关键词的突发检测分析表明，“国家免疫调查”，\'社交媒体\',和“犹豫”是该领域当前的研究前沿。
结论：本研究为获得HPV疫苗知识提供了有用的信息。解决HPV疫苗接种犹豫不决的研究将成为该领域的学术趋势，这可以为未来更广泛和深入的研究提供指导。
目的：我们旨在研究HPV疫苗的开发，直观地分析发展状况，趋势,研究热点,和这个领域的前沿，为其研究提供参考。
方法：文章来自WebofScienceCoreCollection。VOS查看器和CiteSpace软件用于分析出版物增长，国家/地区,机构,日记帐分布，作者,参考，和关键词，并收集突发关键词来展示研究热点。
结果：共获得4831个参考文献，过去十年来，每年的出版物数量不断增加。美利坚合众国在文章百分比方面排名最高。该领域研究出版物数量最多的机构是疾病控制和预防中心。最有生产力和经常被引用的作者是LauriEMarkowitz。该领域出版物最多的杂志是疫苗，最有影响力的杂志是儿科。最常引用的参考文献是“抗女性感染和上皮内瘤变的9价HPV疫苗”。对顶级关键词的突发检测分析表明，“国家免疫调查”，\'社交媒体\',和“犹豫”是该领域当前的研究前沿。
结论：本研究为获得HPV疫苗知识提供了有用的信息。解决HPV疫苗接种犹豫不决的研究将成为该领域的学术趋势，这可以为未来更广泛和深入的研究提供指导。
