关键词: Mohs micrographic surgery (MMS) Slow-Mohs en face section frozen section horizontal section lentigo maligna (MMIS-LM) malignant melanoma in situ modified Mohs permanent section staged excision vertical section wide local excision

Mesh : Humans Hutchinson's Melanotic Freckle / pathology Guideline Adherence Melanoma / pathology Skin Neoplasms / pathology Mohs Surgery / methods Melanoma, Cutaneous Malignant

来  源:   DOI:10.1016/j.jaad.2023.04.072

Abstract:
Malignant melanoma in-situ, lentigo maligna (MMIS-LM) can be successfully treated with several different surgical techniques; however, the literature is inconsistent in defining them.
To comprehensively define and describe the national guideline recommended surgical techniques used to treat MMIS-LM to help clarify and standardize this terminology to ensure compliance with the guidelines.
A targeted literature review was performed from 1990 to 2022 focusing on articles that discussed the national guideline recommended surgical techniques of wide local excision, Mohs micrographic surgery (MMS), modified Mohs surgery, and staged excision/Slow-Mohs for MMIS-LM, as well as the related methods of tissue processing. National Comprehensive Cancer Network and American Academy of Dermatology guidelines were reviewed to identify how the techniques need to be employed to be compliant with guideline recommendations.
We describe the various surgical and tissue processing techniques and discuss advantages and disadvantages of each.
This paper was styled as a narrative review defining and clarifying terminology and technique and does not investigate these topics more broadly.
Understanding the methodology and terminology for these surgical procedures and tissue processing methods is critical so that both general dermatologists and surgeons can employ these techniques effectively for optimal patient care.
摘要:
背景:原位恶性黑色素瘤,可以用几种不同的手术技术成功治疗恶性扁豆(MMIS-LM),然而,文献在定义它们时不一致。
目的:全面定义和描述用于治疗MMIS-LM的国家指南推荐的手术技术,以帮助澄清和标准化该术语,以确保符合指南。
方法:从1990-2022年进行了针对性的文献综述,重点讨论了国家指南推荐的广泛局部切除手术技术,Mohs显微外科手术(MMS),Mohs改良手术,和MMIS-LM的分期切除/慢莫氏,以及组织处理的相关方法。对国家综合癌症网络(NCCN)和美国皮肤病学会(AAD)指南进行了审查,以确定如何使用这些技术才能符合指南建议。
结果:我们描述了各种手术和组织处理技术,并讨论了每种技术的优缺点。
结论:这篇论文的风格是叙述性综述,定义和澄清术语和技术,并没有更广泛地研究这些主题。
结论:了解这些外科手术和组织处理方法的方法和术语是至关重要的,因此一般皮肤科医生和外科医生都可以有效地采用这些技术来实现最佳的患者护理。
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