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Abstract：
Introduction Currently, peripheral nerve block has shown immense potential with effective patient satisfaction. In the event of upper limb surgeries, the supraclavicular brachial plexus approach under ultrasound guidance renders quick and dense anesthesia. In addition, the clinical utility of adjuvants with local anesthetics elicits a good quality of nerve block with improved duration and inset. So the aim of the present study was to compare the block characteristics of dexmedetomidine and dexamethasone during supraclavicular brachial plexus block in patients undergoing upper limb surgeries. Materials and methods The present study was conducted on 100 patients aged 20-60 years with the American Society of Anesthesiologists (ASA)-I and ASA-II classification who were scheduled for upper limb surgeries. These patients were divided equally into two groups, namely group D (who received 20mL of 0.5% bupivacaine + 50 mcg (0.5mL) of dexmedetomidine +1.5mL normal saline) and group X (who received 20mL of 0.5% bupivacaine +8mg of dexamethasone), ensuring a total volume of 22mL administered to both groups. The time of onset and duration of the sensory and motor blocks, as well as the quality of intraoperative analgesia, were assessed. Results The addition of dexmedetomidine (50mcg) and dexamethasone (8mg) to 0.5% bupivacaine ensured a faster onset and prolonged duration of the sensory and motor blocks. Additionally, dexmedetomidine resulted in more prolonged postoperative analgesia, a lower mean visual analog scale score in the first 24 hours, and lesser opioid consumption in 24 hours than dexamethasone. Conclusion Dexmedetomidine is superior to dexamethasone as an adjuvant to bupivacaine during supraclavicular brachial plexus block in patients undergoing upper limb surgeries.
摘要：
导言目前,周围神经阻滞显示出巨大的潜力，有效的患者满意度。如果上肢手术，超声引导下的锁骨上臂丛入路可快速而密集地麻醉。此外,局部麻醉药佐剂的临床应用可以改善神经阻滞的持续时间和插入。因此，本研究的目的是比较右美托咪定和地塞米松在上肢手术患者锁骨上臂丛神经阻滞中的阻滞特征。材料和方法本研究是对100名年龄在20-60岁的患者进行的，这些患者符合美国麻醉医师协会（ASA）-I和ASA-II分类，计划进行上肢手术。这些患者平均分为两组，即D组(接受20mL0.5%布比卡因+50mcg(0.5mL)右美托咪定+1.5mL生理盐水)和X组(接受20mL0.5%布比卡因+8mg地塞米松),确保两组给药总体积为22mL。感觉和运动阻滞的发作时间和持续时间，以及术中镇痛的质量，被评估。结果在0.5％布比卡因中加入右美托咪定（50mcg）和地塞米松（8mg）可确保感觉和运动阻滞的起效更快，持续时间更长。此外,右美托咪定导致更长时间的术后镇痛，在最初的24小时内，平均视觉模拟量表得分较低，24小时内阿片类药物的消费量低于地塞米松。结论右美托咪定辅助应用于上肢手术患者锁骨上臂丛神经阻滞的效果优于地塞米松。
