METHODS: A cross-sectional comparison of the patients who had undergone resection of neurofibroma for NF1. Data regarding patient characteristics and data about operative outcomes were recorded. The definition of intraoperative hemorrhage group was the intraoperative blood loss greater than 200 ml.
RESULTS: Of 94 eligible patients, 44 patients were in the hemorrhage group and 50 patients were in the non-hemorrhage group. Multiple logistic regression analysis demonstrated that the area of excision, classification, surgical site, primary surgical, and organ deformation were significant independent predictors of hemorrhage.
CONCLUSIONS: Early treatment can reduce the tumor cross-sectional area, avoid organ deformation, and reduce intraoperative blood loss. For plexiform neurofibroma or neurofibroma of the head and face, the amount of blood loss should be predicted correctly, and preoperative evaluation and blood preparation should be paid more attention to.
方法:接受NF1切除神经纤维瘤的患者的横断面比较。记录有关患者特征的数据和有关手术结果的数据。术中出血组的定义是术中出血量大于200ml。
结果:在94名符合条件的患者中,出血组44例,非出血组50例。多元logistic回归分析表明,切除面积,分类,手术部位,初级外科,器官变形是出血的独立预测因子。
结论:早期治疗可以减小肿瘤横截面积,避免器官变形,减少术中失血。对于丛状神经纤维瘤或头部和面部的神经纤维瘤,应该正确预测失血量,术前评估和血液准备应更加重视。