Abstract：
Strongyloidiasis is a parasitosis representing a significant public health problem in tropical countries. It is often asymptomatic in immunocompetent individuals but its mortality rate increases to approximately 87% in severe forms of the disease. We conducted a systematic review, including case reports and case series, of Strongyloides hyperinfection and dissemination from 1998 to 2020 searching PubMed, EBSCO and SciELO. Cases that met the inclusion criteria of the Preferred Reported Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist were analysed. Statistical analysis was performed using Fisher\'s exact test and Student\'s t-test and a Bonferroni correction for all the significant values. A total of 339 cases were included in this review. The mortality rate was 44.83%. The presence of infectious complications, septic shock and a lack of treatment were risk factors for a fatal outcome. Eosinophilia and ivermectin treatment were associated with an improved outcome.
摘要：
Strongyiopiasis是一种寄生虫病，代表了热带国家的重大公共卫生问题。它在有免疫能力的个体中通常是无症状的,但是在严重形式的疾病中它的死亡率增加到大约87%。我们进行了系统的审查，包括病例报告和病例系列，从1998年到2020年的类圆线虫过度感染和传播搜索PubMed，EBSCO和SciELO。分析了符合系统评价和荟萃分析（PRISMA）清单首选报告项目纳入标准的病例。使用Fisher精确检验和Studentt检验以及Bonferroni校正对所有显著值进行统计学分析。本综述共纳入339例病例。死亡率为44.83%。感染性并发症的存在，感染性休克和缺乏治疗是致死性结局的危险因素.嗜酸性粒细胞增多和伊维菌素治疗与改善预后相关。
