关键词: India challenges diabetes gaps syndemic tuberculosis

Mesh : Humans India / epidemiology Tuberculosis / epidemiology Diabetes Mellitus / epidemiology therapy Syndemic COVID-19 / epidemiology complications Prevalence Comorbidity

来  源:   DOI:10.1111/1753-0407.13427   PDF(Pubmed)

Abstract:
Both diabetes mellitus (DM) and tuberculosis (TB) are prevalent all across in India. TB-DM comorbidity has emerged as a syndemic and needs more attention in India considering gaps in screening, clinical care, and research. This paper is intended to review published literature on TB and DM in India to understand the burden of the dual epidemic and its trajectory and to obtain perspectives on the gaps, constraints, and challenges in care and treatment of this dual epidemic. A literature search was carried out on PubMed, Scopus, and Google Scholar, using the key words \'Tuberculosis\' OR \'TB\' AND \'Diabetes\' OR \'Diabetes Mellitus\' AND \'India\', focusing on the research published between the year 2000 to 2022. The prevalence of DM is high in patients with TB. Quantitative data on the epidemiological situation of TB/DM in India such as incidence, prevalence, mortality, and management are lacking. During the last 2 years convergence of TB-DM syndemic with the COVID-19 pandemic has increased cases with uncontrolled DM but also made coordinated control of TB-DM operationally difficult and of low effectiveness. Research regarding TB-DM comorbidity is required in the context of epidemiology and management. Detection and bidirectional screening are aggressively warranted. Management of DM in those with TB-DM comorbidity needs more efforts, including training and supervision of frontline workers.
摘要:
糖尿病(DM)和结核病(TB)在印度都很普遍。考虑到筛查方面的差距,TB-DM合并症已成为一种流行病,在印度需要更多关注。临床护理,和研究。本文旨在回顾已发表的有关印度结核病和DM的文献,以了解双重流行病的负担及其轨迹,并获得有关差距的观点,约束,以及这种双重流行病的护理和治疗方面的挑战。在PubMed上进行了文献检索,Scopus,和谷歌学者,使用关键词\'结核病\'或\'结核病\'和\'糖尿病\'或\'糖尿病\'和\'印度\',专注于2000年至2022年之间发表的研究。结核病患者中DM的患病率很高。关于印度结核病/DM流行病学状况的定量数据,如发病率,患病率,死亡率,缺乏管理。在过去的2年中,结核病-DM与COVID-19大流行的融合增加了不受控制的DM病例,但也使结核病-DM的协调控制在操作上很困难且有效性较低。在流行病学和管理的背景下,需要进行有关TB-DM合并症的研究。积极保证检测和双向筛查。结核病-DM合并症患者的DM管理需要更多的努力,包括一线工人的培训和监督。
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