Abstract：
Abstract Background: Staphylococcus lugdunensis is a coagulase-negative staphylococci that is considered normal skin microbiota. It has been described as a cause of soft tissue infections but is not a common micro-organism as the cause of orthopedic surgery-related infections. This study describes the characteristics, treatment, and results of musculoskeletal infection by Staphylococcus lugdunensis treated in our institution. Methods: We performed a descriptive, retrospective observational study. Clinical records of all musculoskeletal infections treated in our department between 2012 and 2020 were reviewed. We selected those patients with a positive monomicrobial culture for Staphylococcus lugdunensis. Risk factors for infection, patient\'s medical records, previous surgery performed, time from surgery to infection, culture antibiogram, antibiotic and surgical treatment for the infection, and recovery rate were registered for the analysis. Results: Of the 1,482 patients with musculoskeletal infections diagnosed in our institution, 22 had a monomicrobial positive culture of Staphylococcus lugdunensis after an orthopedic surgery representing 1.5% of all orthopedic infections. Ten patients underwent arthroplasty, six underwent fractures synthesis, three had foot surgeries, two had anterior cruciate ligament reconstructions, and one had spine surgery. All patients needed surgery and antibiotic treatment with a mean of two surgeries. The most used antibiotic scheme was levofloxacin-rifampicin. The mean follow-up was 36 months. Ninety-six percent of the patients achieved a complete clinical and analytical recovery. Conclusions: Although musculoskeletal infections caused by Staphylococcus lugdunensis are not common, we have observed a statistically significant incidence increase of Staphylococcus lugdunensis in recent years. If managed with appropriately aggressive surgical treatment and correct antibiotic therapy, good results can be obtained.
摘要：
摘要背景：鲁氏葡萄球菌是一种凝固酶阴性的葡萄球菌，被认为是正常的皮肤微生物群。它已被描述为软组织感染的原因，但不是骨科手术相关感染的常见微生物。这项研究描述了特点，治疗,以及在我们机构治疗的卢氏葡萄球菌肌肉骨骼感染的结果。方法：我们进行了描述性的，回顾性观察性研究。回顾了2012年至2020年在我们部门治疗的所有肌肉骨骼感染的临床记录。我们选择了鲁dunensis葡萄球菌抗菌培养阳性的患者。感染的危险因素，病人的医疗记录，以前做过手术,从手术到感染的时间，文化抗菌谱,抗生素和手术治疗感染，和回收率进行了分析。结果：在我们机构诊断的1,482例肌肉骨骼感染患者中，22在骨科手术后具有lugdunensis葡萄球菌的抗菌阳性培养物，占所有骨科感染的1.5％。十名患者接受了关节置换术，六个人进行了骨折合成，三个人做了足部手术,两个人进行了前交叉韧带重建,还有一个做了脊柱手术.所有患者均需要手术和抗生素治疗，平均两次手术。最常用的抗生素方案是左氧氟沙星-利福平。平均随访时间为36个月。96％的患者实现了完全的临床和分析恢复。结论：虽然由卢氏葡萄球菌引起的肌肉骨骼感染并不常见，近年来，我们观察到卢氏葡萄球菌的发病率显着增加。如果采用适当的积极手术治疗和正确的抗生素治疗，可以获得良好的效果。
