Abstract:
Malignant pleural mesothelioma (MPM) is a severe form of cancer that originates from mesothelium cells. Around 54-90% of mesotheliomas are associated with pleural effusions. Brucea Javanica Oil Emulsion (BJOE) is the processed oil derived from the seeds of Brucea javanica, which has shown potential as a treatment option for several types of cancer. Here, we present a case study of a MPM patient with malignant pleural effusion who received intrapleural injection of BJOE. The treatment resulted in the complete response of pleural effusion and chest tightness. While the precise mechanisms underlying the therapeutic effects of BJOE for pleural effusion are not yet fully understood, it has demonstrated a satisfactory clinical response without significant adverse effects.
摘要:
恶性胸膜间皮瘤(MPM)是一种严重的癌症,起源于间皮细胞。大约54-90%的间皮瘤与胸腔积液有关。鸦胆子油乳液(BJOE)是来自鸦胆子种子的加工油,已显示出作为几种癌症的治疗选择的潜力。这里,我们对1例恶性胸腔积液的MPM患者进行了胸腔内注射BJOE的病例研究。治疗导致胸腔积液和胸闷的完全反应。虽然BJOE治疗胸腔积液的确切机制尚未完全了解,它已显示出令人满意的临床反应,没有明显的不良反应。