PDF(Pubmed)
Abstract：
Candida infective endocarditis is a rare but serious entity that often requires aggressive treatment. However, treatment can be challenging in patients infected with drug-resistant fungi and/or with substantial comorbidity. Moreover, recommendations in treatment guidelines for these patients are based on limited clinical data due to their rarity. Here we report a case of Nakaseomyces glabrata (Candida glabrata) prosthetic valve endocarditis in a patient with congenital heart disease. This case illustrates a therapeutic dilemma for Nakaseomyces glabrata prosthetic valve endocarditis and the need for novel antifungal drugs and further clinical studies.
摘要：
念珠菌感染性心内膜炎是一种罕见但严重的实体，通常需要积极的治疗。然而,在感染耐药真菌和/或大量合并症的患者中，治疗可能具有挑战性。此外，这些患者的治疗指南中的建议是基于有限的临床数据,因为这些患者很少见.在这里，我们报告了一例先天性心脏病患者的光滑Nakaseyyces（假丝酵母）人工瓣膜心内膜炎。此病例说明了光滑Nakaseomyces人工瓣膜心内膜炎的治疗困境，以及对新型抗真菌药物和进一步临床研究的需求。
