Abstract:
COVID-19 is a zoonotic coronavirus disease caused by SARS-CoV-2. Its fast spreading by aerosol transmission has made it a highly contagious disease, causing the most recent 2020 pandemic. Although it mainly affects the respiratory system, atypical forms of the disease have been described, including developing an undifferentiated febrile illness without respiratory symptoms, that can represent a diagnostic challenge, mainly in tropical areas where several zoonotic febrile diseases are circulating. Thus, despite the broad clinical spectrum of COVID-19, in the tropics, other zoonotic etiologies should always be considered as differential diagnoses. According to our case reports review, eight different zoonotic febrile diseases misdiagnosed as COVID-19 have been reported in the available scientific literature of four databases. These were only suspected due to the epidemiological history. Thus, making a complete and detailed clinical history of a febrile patient in the tropics is essential to suspect the etiology and request the necessary confirmatory tests. Therefore, COVID-19 must be included as a differential diagnosis of undifferentiated febrile illness in the tropics, but other zoonotic infectious diseases must not be ruled out.
摘要:
COVID-19是由SARS-CoV-2引起的人畜共患冠状病毒病。它通过气溶胶传播的快速传播使其成为一种高度传染性疾病,导致了最近的2020年大流行。虽然它主要影响呼吸系统,已经描述了这种疾病的非典型形式,包括发展为没有呼吸道症状的未分化发热疾病,这可能是一个诊断挑战,主要在热带地区,那里有几种人畜共患的发热疾病正在流行。因此,尽管COVID-19的临床范围很广,但在热带地区,其他人畜共患病因应始终被视为鉴别诊断。根据我们的病例报告审查,在四个数据库的现有科学文献中,已经报道了八种不同的人畜共患高热疾病误诊为COVID-19。这些只是由于流行病学史而被怀疑。因此,对热带地区的发热患者进行完整而详细的临床病史,对于怀疑病因并要求进行必要的确认测试至关重要。因此,COVID-19必须作为热带地区未分化发热疾病的鉴别诊断,但不能排除其他人畜共患传染病。