PDF(Pubmed)
Abstract：
McCune-Albright syndrome (MAS) is a rare genetic disease affecting multiple organs, including endocrine tissues. This endocrinopathy is sometimes responsible for infertility, as it may induce an independent functioning of the ovaries leading to anovulatory cycles. This case report describes the infertility journey of a 22-year-old female who had early puberty and irregular periods with high estrogen and progesterone levels, low FSH and LH (on day 3 of her menstrual cycle), and a multi-cystic right ovary. She received several infertility treatments: initially in vitro oocyte maturation (IVM) followed by cyst transvaginal ultrasound-guided aspiration, all unsuccessful. A right hemi-ovariectomy was performed that eventually restored regular cycles and made it possible to perform ovarian stimulation (OS) and in vitro fertilization (IVF). Live birth was obtained after the first embryo transfer.
摘要：
McCune-Albright综合征（MAS）是一种罕见的遗传性疾病，影响多个器官，包括内分泌组织。这种内分泌病有时会导致不孕症，因为它可能诱导卵巢的独立功能，导致无排卵周期。该病例报告描述了一名22岁女性的不孕症旅程，该女性青春期早，雌激素和孕激素水平高，不规律，低FSH和LH（在月经周期的第3天），和多囊性右卵巢。她接受了几种不孕症治疗：最初是体外卵母细胞成熟（IVM），然后是囊肿经阴道超声引导的抽吸，都不成功。进行了右半卵巢切除术，最终恢复了规律的周期，并有可能进行卵巢刺激（OS）和体外受精（IVF）。在第一次胚胎移植后获得活产。
