关键词: CT colonography Cancer staging Colon cancer Colorectal cancer Computed tomography MRI PET-CT

Mesh : Humans Colorectal Neoplasms / pathology Positron Emission Tomography Computed Tomography Neoplasm Staging Colonic Neoplasms / diagnostic imaging pathology Positron-Emission Tomography Magnetic Resonance Imaging Radiology Fluorodeoxyglucose F18

来  源:   DOI:10.1007/s00261-023-03904-2

Abstract:
Radiologic imaging, especially MRI, has long been the mainstay for rectal cancer staging and patient selection for neoadjuvant therapy prior to surgical resection. In contrast, colonoscopy and CT have been the standard for colon cancer diagnosis and metastasis staging with T and N staging often performed at the time of surgical resection. With recent clinical trials exploring the expansion of the use of neoadjuvant therapy beyond the anorectum to the remainder of the colon, the current and future state of colon cancer treatment is evolving with a renewed interest in evaluating the role radiology may play in the primary T staging of colon cancer. The performance of CT, CT colonography, MRI, and FDG PET-CT for colon cancer staging will be reviewed. N staging will also be briefly discussed. It is expected that accurate radiologic T staging will significantly impact future clinical decisions regarding the neoadjuvant versus surgical management of colon cancer.
摘要:
放射成像,尤其是核磁共振,长期以来一直是直肠癌分期和手术切除前选择新辅助治疗的主要因素。相比之下,结肠镜检查和CT已成为结肠癌诊断和转移分期的标准,T和N分期通常在手术切除时进行。随着最近的临床试验探索将新辅助疗法的使用从肛门直肠扩展到结肠的其余部分,结肠癌治疗的当前和未来状态正在演变,人们对评估放射学在结肠癌原发T分期中可能发挥的作用有了新的兴趣.CT的性能,CT结肠造影,MRI,和FDGPET-CT对结肠癌分期的评估。N分期也将简要讨论。预计准确的放射学T分期将显著影响未来关于结肠癌新辅助治疗与手术治疗的临床决策。
公众号