PDF(Pubmed)
Abstract：
UNASSIGNED: Autoimmune blistering (AIBD) disorders affect mucosae, skin, and appendages. Appendageal involvement has not been studied extensively to date. However, they are important as nail changes are commonly encountered during a flare-up of the disease.
UNASSIGNED: To determine the prevalence and patterns of nail changes in various Immunobullous disorders and to study the relationship between the nail changes and the disease duration and severity.
UNASSIGNED: A cross-sectional study was conducted at the Department of Dermatology, venerology, and leprosy at a tertiary care center in Mumbai.
UNASSIGNED: A cross-sectional study including a total of 74 cases of Immunobullous diseases was conducted and the prevalence of nail changes was determined. The association between the mean number of nail changes and the disease duration and severity was analyzed using ANOVA (Analysis of variance) and unpaired t-test.
UNASSIGNED: The Statistical Package for Social Studies (SPSS) software was used for statistical evaluation.
UNASSIGNED: We found that the prevalence of nail changes was 91%. There was a significant difference in the mean number of nail changes with respect to the severity grades of mucosal involvement in AIBD (P value < 0.05). There was no significant difference in the mean number of nail changes with respect to the severity grades of Pemphigus vulgaris (PV), Pemphigus foliaceous (PF), subepidermal blistering diseases, and the duration of AIBD.
UNASSIGNED: Nails are frequently affected in AIBD. The number of nail changes is related to the severity of mucosal disease but not to duration.
UNASSIGNED: To determine the prevalence and patterns of nail changes in various Immunobullous disorders and to study the relationship between the nail changes and the disease duration and severity.
UNASSIGNED: A cross-sectional study was conducted at the Department of Dermatology, venerology, and leprosy at a tertiary care center in Mumbai.
UNASSIGNED: A cross-sectional study including a total of 74 cases of Immunobullous diseases was conducted and the prevalence of nail changes was determined. The association between the mean number of nail changes and the disease duration and severity was analyzed using ANOVA (Analysis of variance) and unpaired t-test.
UNASSIGNED: The Statistical Package for Social Studies (SPSS) software was used for statistical evaluation.
UNASSIGNED: We found that the prevalence of nail changes was 91%. There was a significant difference in the mean number of nail changes with respect to the severity grades of mucosal involvement in AIBD (P value < 0.05). There was no significant difference in the mean number of nail changes with respect to the severity grades of Pemphigus vulgaris (PV), Pemphigus foliaceous (PF), subepidermal blistering diseases, and the duration of AIBD.
UNASSIGNED: Nails are frequently affected in AIBD. The number of nail changes is related to the severity of mucosal disease but not to duration.
摘要：
■自身免疫性起泡（AIBD）疾病影响粘膜，皮肤,和附属物。迄今为止，尚未广泛研究阑尾受累。然而,它们很重要，因为在疾病发作期间通常会遇到指甲变化。
■确定各种免疫球性疾病中指甲变化的患病率和模式，并研究指甲变化与疾病持续时间和严重程度之间的关系。
■在皮肤科进行了一项横断面研究，venerology,以及孟买三级护理中心的麻风病。
■进行了一项横断面研究，其中包括总共74例免疫性疾病，并确定了指甲变化的患病率。使用ANOVA(方差分析)和非配对t检验分析指甲变化的平均数与疾病持续时间和严重程度之间的关联。
社会研究统计软件包(SPSS)软件用于统计评价。
■我们发现指甲变化的患病率为91％。相对于AIBD中粘膜受累的严重程度，指甲变化的平均数存在显着差异（P值<0.05）。关于寻常型天疱疮（PV）的严重程度，指甲变化的平均数没有显着差异，天疱疮（PF），表皮下起泡疾病，以及AIBD的持续时间。
■指甲在AIBD中经常受到影响。指甲变化的数量与粘膜疾病的严重程度有关，但与持续时间无关。
■确定各种免疫球性疾病中指甲变化的患病率和模式，并研究指甲变化与疾病持续时间和严重程度之间的关系。
■在皮肤科进行了一项横断面研究，venerology,以及孟买三级护理中心的麻风病。
■进行了一项横断面研究，其中包括总共74例免疫性疾病，并确定了指甲变化的患病率。使用ANOVA(方差分析)和非配对t检验分析指甲变化的平均数与疾病持续时间和严重程度之间的关联。
社会研究统计软件包(SPSS)软件用于统计评价。
■我们发现指甲变化的患病率为91％。相对于AIBD中粘膜受累的严重程度，指甲变化的平均数存在显着差异（P值<0.05）。关于寻常型天疱疮（PV）的严重程度，指甲变化的平均数没有显着差异，天疱疮（PF），表皮下起泡疾病，以及AIBD的持续时间。
■指甲在AIBD中经常受到影响。指甲变化的数量与粘膜疾病的严重程度有关，但与持续时间无关。
