UNASSIGNED: A total of 92,795 participants in the Kailuan study were examined and thereafter followed up until 2020. We considered three transitions (from non-CVD events to incident CVD events, from non-CVD events to mortality, and from CVD events to mortality). The multistate lifetable method was applied to estimate the life expectancy.
UNASSIGNED: During a median follow-up of 13 years, 12,541 (13.51%) deaths occurred. Compared with poor CVH, ideal CVH attenuated the risk of incident CVD events and mortality without CVD events by approximately 58% and 27%, respectively. Women with ideal CVH at age 35 had a 5.00 (3.23-6.77) year longer life expectancy free of CVD events than did women with poor CVH metrics. Among men, ideal CVH was associated with a 6.74 (5.55-7.93) year longer life expectancy free of CVD events.
UNASSIGNED: An ideal CVH status is associated with a lower risk of premature mortality and a longer life expectancy, either in the general population or in CVD patients, which are cost-effective ways for personalized medicine of potential CVD patients. Our findings suggest that the promotion of a higher CVH score or ideal CVH status would result in reduced burdens of CVD events and extended disease-free life expectancy, which offered an accurate prediction for primary care following the concept of PPPM/3PM.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s13167-023-00322-8.
■共有92,795名在开uan研究中的参与者接受了检查,然后随访到2020年。我们考虑了三个转变(从非CVD事件到偶发CVD事件,从非CVD事件到死亡率,从CVD事件到死亡率)。多状态寿命方法用于估计预期寿命。
■在13年的中位随访期间,12,541例(13.51%)死亡。与差的CVH相比,理想的CVH将CVD事件的发生率和无CVD事件的死亡率降低了约58%和27%,分别。与CVH指标较差的女性相比,在35岁时具有理想CVH的女性,无CVD事件的预期寿命延长了5.00(3.23-6.77)年。在男性中,理想的CVH与预期寿命延长6.74(5.55~7.93)年无CVD事件相关.
■理想的CVH状态与较低的过早死亡风险和较长的预期寿命相关,无论是普通人群还是心血管疾病患者,这是潜在的心血管疾病患者个性化医疗的经济有效的方法。我们的研究结果表明,促进更高的CVH评分或理想的CVH状态将导致减少CVD事件的负担和延长无病预期寿命。这为遵循PPPM/3PM概念的初级保健提供了准确的预测。
■在线版本包含补充材料,可在10.1007/s13167-023-00322-8获得。