PDF(Pubmed)
Abstract：
UNASSIGNED: The treatment of osseous bone defects created following enucleation of a cyst is an arduous challenge. Autogenous bone grafts despite being the gold standard have various drawbacks such as donor site morbidity, limited availability of bone graft, and increased operative time. Hence, there are various bone grafts which are being investigated which could overcome the limitations of autografts. Thus, this study was conducted to evaluate the efficacy of calcium sulfate (CS), a bone graft substitute, for spontaneous bone regeneration of cystic defects.
UNASSIGNED: The purpose of this study is to evaluate bone formation in odontogenic cystic defects following enucleation and reconstruction with bone graft substitute by three-dimensional radiographic and clinical evaluation.
UNASSIGNED: A total of twenty patients diagnosed with odontogenic cysts were randomly divided into two groups, out of which the study group had undergone enucleation with bone grafting (tobramycin-impregnated CS dihydrate) and the control group had undergone enucleation without bone grafting. The patients were evaluated clinically and radiographically at the 1st, 3rd, 6th, and 12th months postoperatively.
UNASSIGNED: There was no bone formation observed at 1 month postoperative in both the groups. There was a statistically significant higher bone defect reduction observed radiologically on orthopantomogram and computed tomography scan in the study group than the control group at the 3rd, 6th, and 12th months postoperative. The rate of reduction in cystic volume of the study group at the 12th month was 94.4% and in the control group was 37.16%.
UNASSIGNED: Immediate grafting of cystic cavity can avoid complications such as pathological fracture due to less bone support, delayed healing, etc., The utilization of a graft with a property of inducing rapid bone formation should be taken into consideration. The use of CS as a grafting material accelerated the rate of bone regeneration in the cystic defects, with minimal complications.
UNASSIGNED: The purpose of this study is to evaluate bone formation in odontogenic cystic defects following enucleation and reconstruction with bone graft substitute by three-dimensional radiographic and clinical evaluation.
UNASSIGNED: A total of twenty patients diagnosed with odontogenic cysts were randomly divided into two groups, out of which the study group had undergone enucleation with bone grafting (tobramycin-impregnated CS dihydrate) and the control group had undergone enucleation without bone grafting. The patients were evaluated clinically and radiographically at the 1st, 3rd, 6th, and 12th months postoperatively.
UNASSIGNED: There was no bone formation observed at 1 month postoperative in both the groups. There was a statistically significant higher bone defect reduction observed radiologically on orthopantomogram and computed tomography scan in the study group than the control group at the 3rd, 6th, and 12th months postoperative. The rate of reduction in cystic volume of the study group at the 12th month was 94.4% and in the control group was 37.16%.
UNASSIGNED: Immediate grafting of cystic cavity can avoid complications such as pathological fracture due to less bone support, delayed healing, etc., The utilization of a graft with a property of inducing rapid bone formation should be taken into consideration. The use of CS as a grafting material accelerated the rate of bone regeneration in the cystic defects, with minimal complications.
摘要：
■治疗囊肿摘除后产生的骨性骨缺损是一项艰巨的挑战。自体骨移植尽管是金标准有各种缺点，如供体部位的发病率，骨移植物的可用性有限，增加手术时间。因此，目前正在研究的各种骨移植物可以克服自体移植物的局限性。因此，这项研究是为了评估硫酸钙（CS）的疗效，骨移植替代物,用于囊性缺损的自发骨再生。
■这项研究的目的是通过三维影像学和临床评估来评估牙源性囊性缺损在摘除和骨移植替代物重建后的骨形成。
■将20例牙源性囊肿患者随机分为两组,其中，研究组进行了骨移植摘除（妥布霉素浸渍的CS二水合物），对照组进行了无植骨摘除。患者在1日进行了临床和影像学评估，3rd,6th,术后12个月。
■两组术后1个月均未观察到骨形成。在第3天，研究组在端骨图和计算机断层扫描上的放射学观察到的骨缺损减少量明显高于对照组，6th,术后12个月。研究组第12个月的囊性体积减少率为94.4%，对照组为37.16%。
■立即移植囊腔可避免因骨支撑较少而导致病理性骨折等并发症，延迟愈合,等。,应当考虑使用具有诱导快速骨形成的性质的移植物。使用CS作为移植材料加速了囊性缺损的骨再生率，最小的并发症。
■这项研究的目的是通过三维影像学和临床评估来评估牙源性囊性缺损在摘除和骨移植替代物重建后的骨形成。
■将20例牙源性囊肿患者随机分为两组,其中，研究组进行了骨移植摘除（妥布霉素浸渍的CS二水合物），对照组进行了无植骨摘除。患者在1日进行了临床和影像学评估，3rd,6th,术后12个月。
■两组术后1个月均未观察到骨形成。在第3天，研究组在端骨图和计算机断层扫描上的放射学观察到的骨缺损减少量明显高于对照组，6th,术后12个月。研究组第12个月的囊性体积减少率为94.4%，对照组为37.16%。
■立即移植囊腔可避免因骨支撑较少而导致病理性骨折等并发症，延迟愈合,等。,应当考虑使用具有诱导快速骨形成的性质的移植物。使用CS作为移植材料加速了囊性缺损的骨再生率，最小的并发症。
