Abstract：
Infections caused by Robinsoniella peoriensis, particularly bacteremia, are rare, of which only six cases were reported R. peoriensis bloodstream infections. This case report describes an instance of R. peoriensis bacteremia arising while we treated the patient with piperacillin-tazobactam. We treated an 84-year-old female patient with peritoneal carcinoma and febrile neutropenia using piperacillin-tazobactam. The patient\'s fever subsided. However, she developed a fever again on the fourth day of treatment with piperacillin-tazobactam. Blood cultures taken at this time were positive for R. peoriensis. We substituted meropenem and vancomycin for piperacillin-tazobactam, after which the patient improved. We administered meropenem and vancomycin for 17 days. There is currently no appropriate established treatment for R. peoriensis. In this case, we isolated R. peoriensis from blood cultures using piperacillin-tazobactam, although it was susceptible to piperacillin-tazobactam in vitro. Therefore, monotherapy with penicillins, especially piperacillin-tazobactam, may not be sufficient for R. peoriensis infections, although it was susceptible in vitro. Carbapenem may be effective in the treatment of R. peoriensis bloodstream infections.
摘要：
由罗宾逊菌引起的感染，尤其是菌血症,是罕见的，其中只有6例报告了猪头孢的血流感染。此病例报告描述了我们用哌拉西林-他唑巴坦治疗患者时出现的一种情况。我们使用哌拉西林-他唑巴坦治疗了一名84岁的腹膜癌和发热性中性粒细胞减少症女性患者。病人的发烧消退了。然而,在使用哌拉西林他唑巴坦治疗的第四天，她再次发烧。此时采集的血液培养对R.peoriensis呈阳性。我们用美罗培南和万古霉素代替哌拉西林他唑巴坦，之后患者好转。我们给药美罗培南和万古霉素17天。目前没有适当的已确定的治疗方法。在这种情况下,我们用哌拉西林他唑巴坦从血培养物中分离出了波里氏菌，尽管它在体外对哌拉西林-他唑巴坦敏感。因此,用青霉素单药治疗，尤其是哌拉西林他唑巴坦,可能不足以治疗猪瘟病毒感染，尽管它在体外易感。碳青霉烯类可有效治疗R.peoriensis血流感染。
