MEDLINE, Scopus, Clarivate Analytics Web of Science, and the Cochrane Library databases were searched systematically until January 2023, for clinical interventions that investigated the effect of Spirulina supplementation on plasma lipid profile concentrations.
ooled results of 20 studies (with 23 arms and 1076 participants) indicated that Spirulina intervention significantly reduced LDL-C (SMD: -0.6, 95% CI: -0.9, -0.2, P<0.05), TC (SMD: -0.6, 95% CI: -0.9, -0.2, P<0.05) and TG (SMD: -0.6, 95% CI: -0.9, -0.2, P<0.05) levels while HDL-C levels were significantly increased (SMD: 0.3, 95% CI: 0.0, 0.6, P<0.05).
The findings of the present meta-analysis and review show the usefulness of supplementing with Spirulina in improving serum levels of TC, TG, LDL-C, and HDL-C.
方法:MEDLINE,Scopus,ClarivateAnalyticsWebofScience,系统检索CochraneLibrary数据库,直至2023年1月,研究补充螺旋藻对血脂谱浓度影响的临床干预措施.
结果:20项研究(23组和1076名参与者)的总体结果表明,螺旋藻干预显着降低了LDL-C(SMD:-0.6,95%CI:-0.9,-0.2,P<0.05),TC(SMD:-0.6,95%CI:-0.9,-0.2,P<0.05)和TG(SMD:-0.6,95%CI:-0.9,-0.2,P<0.05)水平,而HDL-C水平显着升高(SMD:0.3,95%CI:0.0,0.6,P<0.05)。
结论:本荟萃分析和综述的结果表明,补充螺旋藻可改善血清TC水平,TG,LDL-C,和HDL-C