关键词: Aglycones Enzyme substrates Glycosides Isoflavones β-glucosidase

Mesh : beta-Glucosidase / chemistry Hydrolysis Glycosides / metabolism Glucose / metabolism Pharmaceutical Preparations

来  源:   DOI:10.1016/j.carres.2023.108855

Abstract:
β-glucosidases hydrolyse glycosidic bonds to release non-reducing terminal glucosyl residues from glycosides and oligosaccharides via catalytic mechanisms. It is very well known that the β-glucosidase enzyme is used in biorefineries for cellulose degradation, where β-glucosidases is the rate-limiting enzyme for the final glucose production from cellobiose. The β-glucosidase enzyme is used as a catalyst in other industrial sectors, including pharmaceuticals, breweries, dairy, and food processing. With the aid of β-glucosidase enzymes, cyanogenic glycosides and plant glycosides are transformed into sugar moiety and aglycones. These aglycone compounds are employed as aromatic compounds in the food processing and brewing industries. They are also used as medications and dietary supplements based on their pharmacological qualities. Applications of aglycones and the microbiological sources of β-glucosidase in aglycone production have been discussed in this review.
摘要:
β-葡糖苷酶水解糖苷键以通过催化机理从糖苷和寡糖释放非还原性末端葡糖基残基。众所周知,β-葡萄糖苷酶在生物精炼厂中用于纤维素降解,其中β-葡糖苷酶是从纤维二糖最终产生葡萄糖的限速酶。β-葡萄糖苷酶在其他工业部门用作催化剂,包括药品,啤酒厂,乳制品,和食品加工。在β-葡萄糖苷酶的帮助下,生氰苷和植物苷被转化为糖部分和苷元。这些糖苷配基化合物在食品加工和酿造工业中用作芳族化合物。根据其药理特性,它们也被用作药物和膳食补充剂。本文综述了糖苷配基的应用以及β-葡萄糖苷酶的微生物来源在糖苷配基生产中的应用。
公众号