Mesh : Humans Leprosy, Lepromatous / complications diagnosis drug therapy Erythema Nodosum / diagnosis drug therapy Leprostatic Agents / therapeutic use Drug Therapy, Combination Leprosy / drug therapy Recurrence

来  源:   DOI:10.4269/ajtmh.22-0701   PDF(Pubmed)

Abstract:
Leprosy is a chronic infection caused by Mycobacterium leprae and Mycobacterium lepromatosis that preferentially compromises peripheral nerve, skin, and mucous membranes. Colombia achieved the goal of leprosy elimination in 1997. However, in Urabá (Colombia), there has been an increase in leprosy cases beginning in 2020. This case report shows a leprosy relapse 5 decades after the initial infection debuted as a necrotizing erythema nodosum leprosum. Therefore, long-term follow-up of patients with risk factors for relapse is emphasized, especially those treated before the standard of multidrug therapy (dapsone, clofazimine, and rifampin). This case report stresses the importance the importance of clinical follow-up and surveillance of patients with these events of interest for the public health.
摘要:
麻风病是由麻风分枝杆菌和麻风分枝杆菌引起的慢性感染,优先损害周围神经,皮肤,和粘膜。哥伦比亚在1997年实现了消除麻风病的目标。然而,在乌拉巴(哥伦比亚),从2020年开始,麻风病病例有所增加。此病例报告显示,麻风病在最初感染后5年复发,首次出现坏死性结节性红斑。因此,强调有复发危险因素的患者的长期随访,特别是那些在标准的多药治疗(氨苯砜,氯法齐明,和利福平)。该病例报告强调了对这些关注事件的患者进行临床随访和监测对公共卫生的重要性。
公众号