Abstract：
Background: Alopecia androgenetica is the most common type of hair loss. It is estimated that 60-70% of the world\'s population is affected, with men having a slight advantage. This condition supports a progressive hair thinning in androgen-sensitive zones, as defined by the Hamilton and Norwood classifications for men and Ludwig classifications for women. There are numerous published studies that show the effect of red light (650-675 nm) on hair growth biostimulation. Objective: To validate this correlation, the aim of this study was to assess the efficacy of 675 nm laser emission for the management of alopecia androgenetica in female and male subjects. Methods: A total of 17 subjects (6 women and 11 men) aged from 18 to 65 years, without other comorbidities, with an alopecia androgenetica grade ranges between I-II in women (according to Ludvig scale) and I-II-III in men (according to Hamilton scale) were enrolled in the study between October and December 2021. All patients underwent 10 sessions of 675 nm laser treatment, each lasting 20 min, without the use of concomitant systemic or topical therapies. Results: The results verified at epiluminescence stage, and at the third month of follow-up and at the end of treatment, showed a significant increase in the density of the hair shafts and a reduction of yellow dots and telangiectasias characteristic of alopecia androgenetica. Conclusions: The 675 nm laser showed excellent outcomes resulting in a 60% reduction of the miniaturization process in the treated areas without side effect.
摘要：
背景：雄激素性脱发是最常见的脱发类型。据估计，世界上60-70%的人口受到影响，男人有一点优势。这种情况支持雄激素敏感区的头发逐渐变薄，根据汉密尔顿和诺伍德的男性分类和路德维希的女性分类的定义。有许多已发表的研究显示红光(650-675nm)对毛发生长生物刺激的影响。目的：为了验证这种相关性，这项研究的目的是评估675nm激光发射对女性和男性受试者雄激素性脱发的疗效。方法:研究对象17例(女6例,男11例),年龄18~65岁,没有其他合并症，在2021年10月至12月期间,研究纳入了女性I-II级(根据Ludvig量表)和男性I-II-III级(根据Hamilton量表)的雄激素脱发.所有患者接受了10次675nm激光治疗，每次持续20分钟，不使用伴随的全身或局部治疗。结果：结果在外延发光阶段得到验证，在随访的第三个月和治疗结束时，显示头发干的密度显着增加，并且以雄激素脱发为特征的黄点和毛细血管扩张减少。结论:675nm激光显示出优异的结果,导致治疗区域中的小型化过程减少60%而没有副作用。
