PDF(Pubmed)
Abstract：
Infection with West Nile virus (WNV) is often characterized by a mild febrile illness, but it can progress to meningitis, encephalitis, flaccid paralysis, and respiratory failure. The neuro-ophthalmological manifestations of this disease are uncommonly discussed. This case describes a 49-year-old undomiciled male who developed WNV flaccid paralysis with ophthalmoplegia. His symptoms began with difficulty in walking and progressed over several days to flaccid paralysis and ophthalmoplegia. Cerebrospinal fluid was positive for WNV immunoglobulin M antibodies and electromyography demonstrated acute denervation in several muscle groups. This is an unusual case of neuro-invasive WNV presenting with flaccid paralysis and ophthalmoplegia.
摘要：
感染西尼罗河病毒（WNV）通常以轻度发热疾病为特征，但它可以进展为脑膜炎，脑炎,弛缓性麻痹,和呼吸衰竭。这种疾病的神经眼科表现很少讨论。该病例描述了一名49岁的无住所男性，他因眼肌麻痹而发展为WNV弛缓性麻痹。他的症状始于行走困难，并在几天内发展为弛缓性麻痹和眼肌麻痹。脑脊液对WNV免疫球蛋白M抗体呈阳性，肌电图在几个肌肉群中显示出急性神经支配。这是一例罕见的神经侵袭性WNV，表现为弛缓性麻痹和眼肌麻痹。
