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Abstract：
Gastrointestinal (GI) intestinal stromal tumors account for 60% of mesenchymal GI tract tumors commonly located in the stomach and small intestine, predominantly solid tumors that rarely undergo cystic degeneration. A 65-year-old patient with increasing upper abdominal swelling and a computed tomography scan abdomen showed a large unilocular 17 × 16 × 15 cm lesion. A colossal cystic swelling in the lesser omentum, anterior to the stomach, was found upon exploration. Histopathological examination showed a spindle cell tumor turned out to be CD117 positive and S100 negative on immunostains. The tumor was moderate risk gastric gastrointestinal intestinal stromal tumor (GIST) based on the site; Stomach, Size >10 cm; Mitosis <5/5 mm2 according to risk assessment of GIST, 2006. GISTs are predominantly solid tumors and rarely undergo cystic transformation. The primary differential diagnoses of spindle cell neoplasm are GISTs, Leiomyoma, Leiomyosarcoma and Schwannoma. These spindle cell neoplasms are differentiated by applying a panel of Immunohistochemical stains, CD117, SMA and S100.
摘要：
胃肠道（GI）肠间质瘤占胃肠道间质瘤的60％，通常位于胃和小肠，主要是实体瘤，很少发生囊性变性。一名65岁的患者，上腹部肿胀增加，计算机断层扫描腹部显示出较大的单眼17×16×15cm病变。小网膜有巨大的囊性肿胀，在胃的前面,是在探索中发现的。组织病理学检查显示梭形细胞瘤在免疫染色上为CD117阳性和S100阴性。根据部位，肿瘤为中危胃胃肠道间质瘤(GIST)；胃、尺寸>10cm；根据GIST的风险评估，有丝分裂<5/5mm2，2006.GIST主要是实体瘤，很少进行囊性转化。梭形细胞肿瘤的主要鉴别诊断是GIST，平滑肌瘤,平滑肌肉瘤和神经鞘瘤。这些梭形细胞肿瘤通过应用一组免疫组织化学染色来分化，CD117、SMA和S100。
