METHODS: aMMP-8 POCT samples were collected from patients in an oral and maxillofacial surgery clinic during a one-month period. aMMP-8 levels were analyzed using a chairside lateral-flow immunotest and a digital reader. Clinically relevant patient variables were collected and descriptively evaluated. aMMP-8 levels over 20 ng/ml were considered to be elevated.
RESULTS: A total of 115 patients were interviewed of which 112 agreed to the test (97.4%). Elevated aMMP-8 levels were observed in 58 (51.8%) patients. Bone loss was noted in 75 (67.0%) patients. Of these patients, aMMP-8 levels were elevated in 47 (62.7%) patients. Patients at an increased risk of infection had 35.5% higher aMMP-8 values on average compared to patients with no prior illnesses.
CONCLUSIONS: aMMP-8 POCT provides a non-invasive and reliable method for measuring aMMP-8 levels. Future studies are warranted to assess the clinical relevance between elevated aMMP-8 levels and specific patient groups.
CONCLUSIONS: The rapid availability of the test score allows an immediate impact on treatment planning.
方法:aMMP-8POCT样本是从口腔颌面外科诊所的患者中收集的,为期一个月。使用椅旁侧流免疫检测和数字阅读器分析aMMP-8水平。收集临床相关的患者变量并进行描述性评估。超过20ng/ml的aMMP-8水平被认为是升高的。
结果:共采访了115名患者,其中112名患者同意该测试(97.4%)。在58例(51.8%)患者中观察到aMMP-8水平升高。75例(67.0%)患者出现骨丢失。在这些病人中,47例(62.7%)患者的aMMP-8水平升高。与以前没有疾病的患者相比,感染风险增加的患者的aMMP-8值平均高出35.5%。
结论:aMMP-8POCT提供了一种非侵入性和可靠的测量aMMP-8水平的方法。未来的研究有必要评估aMMP-8水平升高与特定患者组之间的临床相关性。
结论:测试评分的快速可用性可以立即影响治疗计划。