PDF(Pubmed)
Abstract：
The aim of this study was to investigate the value of 3D Statistical Shape Modelling for orthognathic surgery planning. The goal was to objectify shape variations in the orthognathic population and differences between male and female patients by means of a statistical shape modelling method. Pre-operative CBCT scans of patients for whom 3D Virtual Surgical Plans (3D VSP) were developed at the University Medical Center Groningen between 2019 and 2020 were included. Automatic segmentation algorithms were used to create 3D models of the mandibles, and the statistical shape model was built through principal component analysis. Unpaired t-tests were performed to compare the principal components of the male and female models. A total of 194 patients (130 females and 64 males) were included. The mandibular shape could be visually described by the first five principal components: (1) The height of the mandibular ramus and condyles, (2) the variation in the gonial angle of the mandible, (3) the width of the ramus and the anterior/posterior projection of the chin, (4) the lateral projection of the mandible\'s angle, and (5) the lateral slope of the ramus and the inter-condylar distance. The statistical test showed significant differences between male and female mandibular shapes in 10 principal components. This study demonstrates the feasibility of using statistical shape modelling to inform physicians about mandible shape variations and relevant differences between male and female mandibles. The information obtained from this study could be used to quantify masculine and feminine mandibular shape aspects and to improve surgical planning for mandibular shape manipulations.
摘要：
这项研究的目的是研究3D统计形状建模对正颌手术计划的价值。目标是通过统计形状建模方法来客观化正颌人群的形状变化以及男女患者之间的差异。包括2019年至2020年在格罗宁根大学医学中心开发3D虚拟手术计划（3DVSP）的患者的术前CBCT扫描。自动分割算法用于创建下颌骨的3D模型，通过主成分分析建立统计形状模型。进行非配对t检验以比较男性和女性模型的主要成分。共纳入194名患者（130名女性和64名男性）。下颌形状可以通过前五个主要成分直观地描述：（1）下颌支和髁的高度，(2)下颌骨前角的变异,（3）下颌支的宽度和前/后投影，(4)下颌骨角度的横向投影，（5）支的横向坡度和髁间距离。统计检验显示，男性和女性下颌形状在10个主成分上存在显着差异。这项研究证明了使用统计形状建模来告知医生有关下颌骨形状变化以及男女下颌骨之间相关差异的可行性。从这项研究中获得的信息可用于量化男性和女性下颌形状方面，并改善下颌形状操作的手术计划。
