PDF(Pubmed)
Abstract：
BACKGROUND: One of the most severe complications of liposuction and fat grafting is pulmonary fat embolism (PFE). However, most healthcare workers are not familiar with PFE. We performed a systematic review to describe the details of PFE.
METHODS: PubMed, EMBASE, and Google Scholar were searched up to October 2022. Further analysis focused on clinical, diagnostic, and outcome parameters.
RESULTS: A total of 40 patients from 19 countries were included. Chest computed tomography (CT) yielded 100% accuracy in the diagnosis of PFE. More than 90% of the deceased died within 5 days after surgery, and in 69% of patients, onset of symptoms occurred within 24 h after surgery. The proportions of patients who required mechanical ventilation, had a cardiac arrest event, or died among all patients and among those whose onset of symptoms occurred within 24 h after surgery were 76%, 38%, and 34% versus 86%, 56%, and 54%, respectively.
CONCLUSIONS: The earlier the onset of symptoms was, the more severe the clinical course was. Once a patient presents with PFE-related symptoms, surgery should be halted, supportive care initiated, and chest CT used to diagnose PFE. According to our review results, if a patient with PFE survives the initial episode without permanent sequelae, a complete recovery can be anticipated.
METHODS: PubMed, EMBASE, and Google Scholar were searched up to October 2022. Further analysis focused on clinical, diagnostic, and outcome parameters.
RESULTS: A total of 40 patients from 19 countries were included. Chest computed tomography (CT) yielded 100% accuracy in the diagnosis of PFE. More than 90% of the deceased died within 5 days after surgery, and in 69% of patients, onset of symptoms occurred within 24 h after surgery. The proportions of patients who required mechanical ventilation, had a cardiac arrest event, or died among all patients and among those whose onset of symptoms occurred within 24 h after surgery were 76%, 38%, and 34% versus 86%, 56%, and 54%, respectively.
CONCLUSIONS: The earlier the onset of symptoms was, the more severe the clinical course was. Once a patient presents with PFE-related symptoms, surgery should be halted, supportive care initiated, and chest CT used to diagnose PFE. According to our review results, if a patient with PFE survives the initial episode without permanent sequelae, a complete recovery can be anticipated.
摘要：
背景：吸脂术和脂肪移植最严重的并发症之一是肺脂肪栓塞（PFE）。然而,大多数医护人员不熟悉PFE。我们进行了系统评价以描述PFE的细节。
方法：PubMed，EMBASE,和谷歌学者被搜索到2022年10月。进一步的分析集中在临床上，诊断,和结果参数。
结果：共纳入来自19个国家的40名患者。胸部计算机断层扫描（CT）在PFE的诊断中具有100％的准确性。超过90%的死者在手术后5天内死亡,在69%的患者中，症状出现在手术后24小时内。需要机械通气的患者比例，有心脏骤停事件,在所有患者中以及在手术后24小时内出现症状的患者中，或死亡的占76％，38%,34%对86%，56%,54%,分别。
结论：症状发作越早，临床过程越严重。一旦患者出现PFE相关症状，手术应该停止，开始支持性护理，胸部CT用于诊断PFE。根据我们的审查结果,如果患有PFE的患者在最初的发作中幸存下来而没有永久性后遗症，可以预期完全恢复。
方法：PubMed，EMBASE,和谷歌学者被搜索到2022年10月。进一步的分析集中在临床上，诊断,和结果参数。
结果：共纳入来自19个国家的40名患者。胸部计算机断层扫描（CT）在PFE的诊断中具有100％的准确性。超过90%的死者在手术后5天内死亡,在69%的患者中，症状出现在手术后24小时内。需要机械通气的患者比例，有心脏骤停事件,在所有患者中以及在手术后24小时内出现症状的患者中，或死亡的占76％，38%,34%对86%，56%,54%,分别。
结论：症状发作越早，临床过程越严重。一旦患者出现PFE相关症状，手术应该停止，开始支持性护理，胸部CT用于诊断PFE。根据我们的审查结果,如果患有PFE的患者在最初的发作中幸存下来而没有永久性后遗症，可以预期完全恢复。
